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2-Bromo-4-(bromomethyl)pyridine

2-Bromo-4-(bromomethyl)pyridine structure

2-Bromo-4-(bromomethyl)pyridine 

structure
  • CAS No:

    83004-14-2

  • Formula:

    C6H5Br2N

  • Chemical Name:

    2-Bromo-4-(bromomethyl)pyridine

  • Synonyms:

    Pyridine,2-bromo-4-(bromomethyl)-;2-Bromo-4-(bromomethyl)pyridine;2-Bromo-4-bromomethylpyridine

  • Categories:

    Pharmaceutical Intermediates  >  Antispasticity Agents

2-Bromo-4-(bromomethyl)pyridine Basic Attributes

251

250.92

DTXSID40513841

2933399090

Characteristics

12.9

2.4

1.955g/cm3

298.8ºC at 760 mmHg

134.5ºC

1.613

2-Bromo-4-(bromomethyl)pyridine Use and Manufacturing

To the solution of i (18 g, 95.74 mmol) in toluene (180 mL) was added dropwise phosphorous tribromide (13.4 mL, 143.62 mmol) at 0° C. under inert atmosphere. A mixture of 4-methyl-2-(methylthio)-4H- thiazolo[5', 4':4, 5]pyrrolo[2, 3-d]pyridazin-5(6H)-one (lOOmg, 0.40 mmol), and K2C03 (164 mg, 1.19 mmol) in DMF (8 mL) was stirred at 60 C for 2 nr., followed by addition of a solution of

Computed Properties

Molecular Weight:250.92
XLogP3:2.4
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:250.87682
Monoisotopic Mass:248.87887
Topological Polar Surface Area:12.9
Heavy Atom Count:9
Complexity:87.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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