CAY10657
-
CAY10657
structure -
-
CAS No:
494772-86-0
-
Formula:
C17H20N4O3S
-
Chemical Name:
CAY10657
-
Synonyms:
3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide;AZ-TAK1 Inhibitor;CAY10657;MLS006010842;SCHEMBL1928700;CHEMBL3182420;DTXSID20433477;ZINC34055196;3-(carbamoylamino)-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide;3-[(Aminocarbonyl)amino]-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide
-
CAS No:
CAY10657 Use and Manufacturing
3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide is a transforming growth factor (TGF)-β-activated kinase 1 (TAK-1) inhibitor. 3-[(Aminocarbonyl)amino]-5-[4-(4-morpholinylmethyl)phenyl]-2-thiophenecarboxamide has potential use in the treatment of certain lymphomas that are particularly susceptible to TAK1 inhibitors such as B cell tumors, solid tumors, or T cell leukemias.
Computed Properties
Molecular Weight:360.4
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:360.12561169
Monoisotopic Mass:360.12561169
Topological Polar Surface Area:139
Heavy Atom Count:25
Complexity:479
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes