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Carbomer

Carbomer structure

CAS No:
54182-57-9
Chemical Name:
Carbomer
Synonyms:
Carbomer 980 940;Gel stock solution product description;Karbomer;Carbomer ISO 9001：2015 REACH;Capom 980;high qualtiy Carbomer
Categories:
Active Pharmaceutical Ingredients > Other Chemical Drugs

Description

Carbomer is a polymer with the formula (CH2-CHCO2H)n. It is a derivative of acrylic acid (CH2=CHCO2H). In addition to the homopolymers, a variety of copolymers and crosslinked polymers, and partially deprotonated derivatives thereof are known and of commercial value. In a water solution at neutral pH, PAA is an anionic polymer, i.e., many of the side chains of PAA lose their protons and acquire a negative charge. Partially or wholly deprotonaated PAAs are polyelectrolytes, with the ability to absorb and retain water and swell to many times their original volume. These properties - acid-base and water-attracting - are the bases of many applications.

Carbomer Basic Attributes

Molecular Weight：

Exact Mass：

72.021129

EC Number：

618-347-7

Characteristics

PSA：

37.3

XLogP3：

0.35

Appearance：

Acrylic acid is a colorless liquid with a distinctive acrid odor. Flash point 130°F. Boiling point 286°F. Freezing point 53°F. Corrosive to metals and tissue. Prolonged exposure to fire or heat can cause polymerization. If polymerization takes place in a closed container, violent rupture may occur. The inhibitor (usually hydroquinone) greatly reduces the tendency to polymerize.

Density：

1.0497 at 68 °F (USCG, 1999)

Melting Point：

55 °F (NTP, 1992)

Boiling Point：

286 °F at 760 mm Hg (NTP, 1992)

Water Solubility：

greater than or equal to 100 mg/mL at 63° F (NTP, 1992)

Vapor Pressure：

3.2 mm Hg at 68 °F ; 5 mm Hg at 81.1° F (NTP, 1992)

Odor：

Acrid odor and fumes

PH：

pH = 3 (approximately)

PKA：

4.26(at 25 °C)

Safety Information

Stability/Shelf Life：

Stable under recommended storage conditions. Contains the following stabilizer(s): Mequinol (>/=0.018 -

Carbomer Use and Manufacturing

Mainly used as controlled-release drugs made of sustained-release materials, and external drugs as carrier matrix

Drug Function and Efficacy

Thickening agent, stabilizer, forms gels in aqueous solutions

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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