4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
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![4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/9ced1e19b8824d7cb1197aaa302948bc.png "4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one")
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
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CAS No:
191219-80-4
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Formula:
C17H16ClN3O
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Chemical Name:
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
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Synonyms:
Pyrido[2,3-d]pyrimidin-2(1H)-one,4-(3-chlorophenyl)-1,7-diethyl-;4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one;YM 976
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CAS No:
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one Basic Attributes
313.78
313.78
DTXSID70424991
Characteristics
45.6
4
pale yellow solid
1.27±0.1 g/cm3(Predicted)
132.7-134.0 °C(lit.)
485.4±55.0 °C(Predicted)
247.4ºC
1.638
DMSO: 16 mg/mL
2-8°C
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one Use and Manufacturing
Orally active PDE4 inhibitor (IC 50 = 2.2 nM). Low emetogenic activity, suggested to be due to poor brain penetration.
Guide of 4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
SDSRequest for Quotation