5-Chloromethyl-1H-tetrazole
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5-Chloromethyl-1H-tetrazole
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CAS No:
55408-11-2
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Formula:
C2H3ClN4
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Chemical Name:
5-Chloromethyl-1H-tetrazole
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Synonyms:
5-CHLOROMETHYL-2H-TETRAZOLE;5-CHLOROMETHYL-1(2)H-TETRAZOLE;5-CHLOROMETHYL-1H-TETRAZOLE;5-CHLOROMETHYL-1H-TETRAZOLE, 98+%;5-chloromethyl Tetrazol;5-Chlromethyl-1H-tetrazole;2H-Tetrazole, 5-(chloromethyl)-;5-(chloroMethyl)-1H-1,2,3,4-tetrazole
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CAS No:
Safety Information
Xi
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
5-Chloromethyl-1H-tetrazole Use and Manufacturing
Preparation of 50ml three-necked flask was charged with 2.85gN- (4-cyclopropylnaphthyl-1-yl) -2-formylhydrazino-1-thiocarboxamide, 1.4g of 5- (chloromethyl) -1H-tetrazole, 2.5g of triethylamine, 20ml of N, N-dimethylformamide, reaction at 40 C for 8h, confirmed by TLCEnd of reaction. After the reaction, the reaction solution was added to water to precipitate a solid. After filtration, the filter cake was washed with water and then the volume ratio was 25:A mixed solution of 75 ethyl acetate and n-heptane was recrystallized, and the wet product was dried at 50 C. for 8 hours to obtain 3.1 g of a solid with a yield of 88%. HPLCPurity 98.5%.General procedure: A stirred mixture of5(1.20 g, 3mmol), A mixture of 6-mercapto-4-(trifluoromethyl)pyridin-2(1H)-one (80 mg, 0.41 mmol),
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