 Home > Encyclopedia > 5-CHLORO-2'-DEOXYCYTIDINE

5-CHLORO-2'-DEOXYCYTIDINE

5-CHLORO-2'-DEOXYCYTIDINE structure

CAS No:
32387-56-7
Formula:
C9H12ClN3O4
Chemical Name:
5-CHLORO-2'-DEOXYCYTIDINE
Synonyms:
5-CHLORO-2'-DEOXYCYTIDINE;Cytochlor
Categories:
Biochemical Engineering > Saccharides

Description

Cytochlor has been used in trials studying the treatment of Head and Neck Cancer and Brain and Central Nervous System Tumors.|Cytochlor is a radio-sensitizing pyrimidine nucleoside with potential antineoplastic activity. Cytochlor is metabolized first to a phosphate derivative, CldCMP, by the enzyme deoxycytidine kinase and then to the active uracyl derivative, CldUMP, by the enzyme dCMP deaminase; deoxycytidine kinase and dCMP deaminase have been found in abnormally high concentrations in most cancers. CldUMP, the active metabolite, incorporates into DNA and, upon exposure to radiation, induces the formation of uracil radicals and double-strand DNA breaks. (NCI04)

5-CHLORO-2'-DEOXYCYTIDINE Basic Attributes

Molecular Weight：

261.66228

Exact Mass：

261.052

UNII：

J14D49ZN55

DSSTox ID：

DTXSID40186099

NCI Thesaurus Code：

C28950

Characteristics

PSA：

108

XLogP3：

-0.9

Density：

1.86g/cm3

Boiling Point：

497.9ºC at 760mmHg

Flash Point：

254.9ºC

Refractive Index：

1.735

Storage Conditions：

2-8°C

Drug Information

MeSH Entry Terms：

2'-deoxy-5-chlorocytidine

Computed Properties

Molecular Weight:261.66
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:261.0516336
Monoisotopic Mass:261.0516336
Topological Polar Surface Area:108
Heavy Atom Count:17
Complexity:398
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 5-CHLORO-2'-DEOXYCYTIDINE

Compound Net Biotechnology Inc. Contact Supplier

CN
2 YRS

Business licensed Certified factory

Manufactory Supplier of 4-(Pentafluorothio)aniline,Pentafluoro,Pentafluorothio,Pentafluorosulfur,[4-(bromomethyl)phenyl]-pentafluoro-lambda6-sulfane,[4-(pentafluoro-sulfanyl)phenyl]acetic acid

32387-56-7 4-amino-5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

CAS No.: 32387-56-7

Grade: Industrial Grade

Content: 95%

Inquiry

Learn More Other Chemicals

5'-deoxy-5'-thioinosine 5'-monophosphate

21959-63-7
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone

22003-30-1
5'-azacytidine5'-monophosphate

2226-72-4
Decarboxylated AdoMet Formula

22365-13-5
2′-Deoxy-6-thioinosine Formula

2239-64-7
Quercetin 3-glucuronide Formula

22688-79-5
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(methylamino)pyrimidin-2-one Structure

22882-02-6
Sucrose Structure

57-50-1
What is C18Dihydroceramide

2304-80-5
What is [5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl adamantane-1-carboxylate

23113-01-1

Hot Searches: tripotassium phosphate; acetic acid chemical formula; tert-butyl alcohol; pentanol; acrylic polymer; methanal

Guide of 5-CHLORO-2'-DEOXYCYTIDINE

Description
Basic Attributes
Characteristics
Drug Information
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

5-CHLORO-2'-DEOXYCYTIDINE

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.