10'-desmethoxystreptonigrin
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10'-desmethoxystreptonigrin
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CAS No:
136803-89-9
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Formula:
C24H20N4O7
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Chemical Name:
10'-desmethoxystreptonigrin
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Synonyms:
10'-desmethoxystreptonigrin;DesMethoxystreptonigrin, 10'-
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CAS No:
10'-desmethoxystreptonigrin Use and Manufacturing
10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.
Computed Properties
Molecular Weight:476.4
XLogP3:1.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:5
Exact Mass:476.13319899
Monoisotopic Mass:476.13319899
Topological Polar Surface Area:188
Heavy Atom Count:35
Complexity:895
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes