3,4-DICHLOROPHENYL HYDROXY UREA

The preparation method is to add water and hydroxylamine sulfate to the reaction kettle at the same time, start stirring, and cool to (20±5)℃, add sodium hydroxide aqueous solution dropwise, add it in about 1 hour, and measure the pH of the solution=7.5～7.9. At this time, 10% 3, 4-dichlorophenyl isocyanate toluene solution was added dropwise, the temperature was controlled at (30±2)°C, the dropping was completed in about 1.5 hours, and the stirring reaction was continued for 2 hours, standing for 2 hours, and layering. The upper toluene clear liquid is pumped and recovered, and the lower material is added with water and stirred to obtain a solid, which is centrifuged and filtered, and the obtained solid is dried to obtain a finished product.

3,4-Dichlorophenyl hydroxyurea is an intermediate of the herbicide Rifolone.

Molecular Weight:221.04
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:219.9806328
Monoisotopic Mass:219.9806328
Topological Polar Surface Area:66.6
Heavy Atom Count:13
Complexity:203
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes