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Home > Encyclopedia > COX-2 INHIBITOR I

COX-2 INHIBITOR I

COX-2 INHIBITOR I structure

COX-2 INHIBITOR I 

structure
  • CAS No:

    416901-58-1

  • Formula:

    C18H16ClNO4S

  • Chemical Name:

    COX-2 INHIBITOR I

  • Synonyms:

    METHYL [5-METHYLSULFONYL-1-(4-CHLOROBENZYL)-1H-2-INDOLYL]CARBOXYLATE;LM-1685;COX-2 INHIBITOR I

Description

LM-1685 is an indolyl carboxylate ester that is methyl 1H-indole-2-carboxylate substituted by a 4-chlorobenzyl group at position 1 and a methylsulfonyl group at position 5. It acts as a selective inhibitor of cyclooxygenase 2. It has a role as a cyclooxygenase 2 inhibitor. It is an indolyl carboxylate ester, a sulfone, a member of monochlorobenzenes and a methyl ester.

COX-2 INHIBITOR I Basic Attributes

377.84

377.049

Characteristics

73.8

3.6

Drug Information

LM-1685

Computed Properties

Molecular Weight:377.8
XLogP3:3.6
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:377.0488569
Monoisotopic Mass:377.0488569
Topological Polar Surface Area:73.8
Heavy Atom Count:25
Complexity:582
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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