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Dexamethasone palmitate

Dexamethasone palmitate structure

CAS No:
14899-36-6
Formula:
C38H59FO6
Chemical Name:
Dexamethasone palmitate
Synonyms:
Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-,(11β,16α)-;Pregna-1,4-diene-3,20-dione,9-fluoro-11β,17,21-trihydroxy-16α-methyl-,21-palmitate;Palmitic acid,21-ester with 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione;(11β,16α)-9-Fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione;Dexamethasone 21-palmitate;Dexamethasone palmitate;Limethason;Lipotalon;Limethasone;80950-33-0
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Colourless Thick Oil

Dexamethasone palmitate is an organic molecular entity.

Dexamethasone palmitate Basic Attributes

Molecular Weight：

630.87

Exact Mass：

630.87

UNII：

601XWN7060

DSSTox ID：

DTXSID8022903

Characteristics

PSA：

101

XLogP3：

10.40

Density：

1.12

Melting Point：

60-65 °C

Boiling Point：

710.1±60.0 °C(Predicted)

Flash Point：

383.2±32.9 °C

Refractive Index：

1.537

Storage Conditions：

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Safety Information

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 9 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

dexamethasone 21-palmitate

Dexamethasone palmitate Use and Manufacturing

A corticosteroid prodrug for the treatment of eye disorders.

Computed Properties

Molecular Weight:630.9
XLogP3:9.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:18
Exact Mass:630.42956776
Monoisotopic Mass:630.42956776
Topological Polar Surface Area:101
Heavy Atom Count:45
Complexity:1130
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

No specific description provided

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Dexamethasone palmitate

Dexamethasone Palmitate Injection
Specifications	1ml:4mg (based on C38H59FO6)
Manufacturer	Beijing Tobishi Pharmaceutical Co., Ltd.

Dexamethasone Palmitate Injection
Specifications	1ml:4mg (as dexamethasone palmitate)

See More Related Drugs

Registered Holders

Cavendish (Taizhou) Pharmaceutical Co., Ltd.

China
Active
Jiangsu GRAND Xianle Pharmaceutical Co., Ltd.

China
Active
Henan LIHUA Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Dexamethasone palmitate

Jinan HaiFang Biotechnology Co., LTD Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Pharmaceutical Intermediates

Inhibitor Lipotalon CAS No. 14899-36-6 Qualified Manufacture and Supplier 99% White Powder HaiZheng

CAS No.: 14899-36-6

Grade: Pharmaceutical Grade

Content: 99%

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