Deferitrin
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Deferitrin
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CAS No:
239101-33-8
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Formula:
C11H11NO4S
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Chemical Name:
Deferitrin
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Synonyms:
Deferitrin;Deferitrin (GT-56-252);4,5-Dihydro-2-(2,4-dihydroxyphenyl)-4-methylthiazol-4-(S)-carboxylic acid;GT 56-252
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CAS No:
Description
Deferitrin is under investigation in clinical trial NCT00069862 (Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-thalassemia).
Characteristics
115.42000
-0.13
1.5±0.1 g/cm3
281-283℃ (decomposition)
525.8±60.0 °C at 760 mmHg
271.8±32.9 °C
1.683
Deferitrin Use and Manufacturing
Deferitrin is a tridentate oral chelator intended for use in the primary treatment of iron overload resulting from transfusion therapy.
Human drugs -> Rare disease (orphan)
Computed Properties
Molecular Weight:253.28
XLogP3:1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:253.04087901
Monoisotopic Mass:253.04087901
Topological Polar Surface Area:115
Heavy Atom Count:17
Complexity:359
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes