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Home > Encyclopedia > (11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al

(11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al

(11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al structure

(11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al 

structure
  • CAS No:

    14760-49-7

  • Formula:

    C21H28O5

  • Chemical Name:

    (11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al

  • Synonyms:

    Pregn-4-en-21-al,11,17-dihydroxy-3,20-dioxo-,(11β)-;Pregn-4-en-21-al,11β,17-dihydroxy-3,20-dioxo-;4-Pregnen-21-al,11,17-dihydroxy-3,20-dioxo-;(11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al;Cortisol-21-aldehyde;Cortisol,21-dehydro-;21-Dehydrocortisol;11β,17-Dihydroxy-3,20-dioxopregn-4-en-21-al;Dehydrocortisol;11β,17-Dihydroxy-4-pregnene-3,20,21-trione;NSC 15472

Description

Off-White to Pale Yellow SolidChEBI: A C21-steroid that is cortisol in which the 21-hydroxy group has been oxidised to the corresponding aldehyde.


21-dehydrocortisol is a C21-steroid that is cortisol in which the 21-hydroxy group has been oxidised to the corresponding aldehyde. It is a 21-oxo steroid, a 20-oxo steroid, a 3-oxo-Delta(4) steroid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a C21-steroid, a steroid aldehyde and a tertiary alpha-hydroxy ketone. It derives from a progesterone. It derives from a hydride of a 5alpha-pregnane.

(11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al Basic Attributes

378.4593

360.44

XT2H26EPI2

15472

Characteristics

91.7

1.9

1.28±0.1 g/cm3(Predicted)

154-156°C

536.1±50.0 °C(Predicted)

292.1ºC

1.586

-20°C Freezer

9.95E-14mmHg at 25°C

Drug Information

21-dehydrocortisol

(11β)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-al Use and Manufacturing

A degradation product of Hydrocortisone (H714615).

Computed Properties

Molecular Weight:360.4
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:360.19367399
Monoisotopic Mass:360.19367399
Topological Polar Surface Area:91.7
Heavy Atom Count:26
Complexity:711
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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