DICHLORO(2Z)-2-[(4-OXO-4H-1-BENZOPYRAN-3-YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE COPPER COMPLEX
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DICHLORO(2Z)-2-[(4-OXO-4H-1-BENZOPYRAN-3-YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE COPPER COMPLEX
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CAS No:
902779-59-3
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Formula:
C11H9N3O2S.Cl2Cu
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Chemical Name:
DICHLORO(2Z)-2-[(4-OXO-4H-1-BENZOPYRAN-3-YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE COPPER COMPLEX
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Synonyms:
FPA 124;HMS3677F22;AKOS024457338
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CAS No:
Description
FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis[1][2].
DICHLORO(2Z)-2-[(4-OXO-4H-1-BENZOPYRAN-3-YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE COPPER COMPLEX Basic Attributes
381.729
379.90900
Computed Properties
Molecular Weight:381.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:379.908850
Monoisotopic Mass:379.908850
Topological Polar Surface Area:109
Heavy Atom Count:20
Complexity:395
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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DICHLORO(2Z)-2-[(4-OXO-4H-1-BENZOPYRAN-3-YL)METHYLENE]HYDRAZINECARBOTHIOAMIDE COPPER COMPLEX
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