 Home > Encyclopedia > Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate

Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate

Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate structure

CAS No:
53554-29-3
Formula:
C8H10N2O3S
Chemical Name:
Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate
Synonyms:
5-Pyrimidinecarboxylic acid,1,6-dihydro-2-(methylthio)-6-oxo-,ethyl ester;5-Pyrimidinecarboxylic acid,1,4-dihydro-2-(methylthio)-4-oxo-,ethyl ester;5-Pyrimidinecarboxylic acid,4-hydroxy-2-(methylthio)-,ethyl ester;Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate;Ethyl 2S-methyl-4-hydroxypyrimidine-5-carboxylate;2-Methylmercapto-4-hydroxy-5-carbethoxypyrimidine;NSC 104155;NSC 43816;4-Hydroxy-2-(methylsulfanyl)pyrimidine-5-carboxylic acid ethyl ester;4-Hydroxy-2-methylthiopyrimidine-5-carboxylic acid ethyl ester;1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidinecarboxylic acid ethyl ester
Categories:
Pharmaceutical Intermediates > Cardiovascular Agents

Request for Quotation

Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate Basic Attributes

Molecular Weight：

214.24

Exact Mass：

214.24

EC Number：

633-406-7

NSC Number：

43816

DSSTox ID：

DTXSID80286103

HScode：

2933599090

Characteristics

PSA：

93.1

XLogP3：

0.6

Density：

1.4±0.1 g/cm3

Melting Point：

132-133 °C

Boiling Point：

340.4°C at 760 mmHg

Flash Point：

155.7±30.7 °C

Refractive Index：

1.601

Safety Information

Hazard category：

IRRITANT

Marks：

Hazard note：

Irritant

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate Use and Manufacturing

To a solution of sodium ethoxide (1.36 g, 20.0 mmol) in ethanol (15 mL) was added S-methylisothiourea sulfate (5.57 g, 40.0 mmol) at 0 °C. After a few minutes, diethyl ethoxymethylenemalonate (4.00 mL, 19.8 mmol) was added. After stirring at 0 °C for 3 h, a solution of sodium ethoxide (1.36 g, 20.0 mmol) in ethanol (15 mL) was added. The resulted solution was stirred at room temperature overnight. Ethanol was removed under reduced pressure and the pale yellow residue was dissolved in water. After filtration, the aqueous filtrate was washed with ether and acidified with acetic acid (10 mL). The organic materials were extracted with CHCl

Computed Properties

Molecular Weight:214.24
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:214.04121336
Monoisotopic Mass:214.04121336
Topological Polar Surface Area:93.1
Heavy Atom Count:14
Complexity:323
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate

Honour Enterprise Company Limited Contact Supplier

CN
4 YRS

Business licensed

Trader Supplier of Semaglutide,Tirzepatide,API,Enzyme

More than 15 years GMP Factory Suppy 99.5% 1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidine-carboxylic acid ethyl ester Medical Grade CAS53554-29-3

CAS No.: 53554-29-3

Grade: Pharmaceutical Grade

Content: 99.5%

Inquiry
NANTONG REFORM PETRO-CHEMICAL CO.,LTD Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Flavors & Fragrances,Catalyst & Auxiliary,Intermediates,Dyes & Pigments,Inorganic Chemistry,petro chemicals,Surfactant,Food Additives,Water Treatment Chemicals

1,4-Dihydro-2-(methylthio)-4-oxo-5-pyrimidine-carboxylateacidethylester

CAS No.: 53554-29-3

Grade: Industrial Grade

Content: 99%

Inquiry

Latest News on Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate

Learn More Other Chemicals

Cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, ethyl ester, (1alpha,3R,4alpha,5R)- (9CI)

463325-95-3
Cyclopropanecarboxylic acid, 1-formyl-2-methyl-, ethyl ester (9CI)

260261-27-6
3-CYCLOPROPYL-2-METHYL-3-OXO-PROPIONIC ACID ETHYL ESTER

21741-37-7
Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, ethyl ester, (1R,2R)-rel- (9CI) Formula

669058-57-5
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, (1R,2S)-rel- (9CI) Formula

213316-32-6
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, hydrochloride (9CI) Formula

681807-60-3
3-Cyclopentene-1-carboxylic acid, 1-(chlorocarbonyl)-, ethyl ester (9CI) Structure

76910-09-3
Cyclopropanecarboxylic acid, 2-propyl-, ethyl ester, (1R,2S)- (9CI) Structure

492468-18-5
What is Cyclopentanecarboxylic acid, 2-(formylhydrazono)-, ethyl ester, (Z)- (9CI)

163352-99-6
What is 2-[(2,6-Dichlorophenyl)sulfonyl]acetic acid ethyl ester

1154228-17-7

Hot Searches: cyanimide; calcium sulfate; methylenediphenyl diisocyanate; d2o; ammonium sulphate fertilizer price; research peptide tirzepatide for sale

Guide of Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate

Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

Ethyl 1,6-dihydro-2-(methylthio)-6-oxo-5-pyrimidinecarboxylate

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.