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Home > Encyclopedia > 5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID

5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID

5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID structure

5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID 

structure
  • CAS No:

    98948-82-4

  • Formula:

    C10H5NO6

  • Chemical Name:

    5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID

  • Synonyms:

    5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID;4,6-dihydroxy-5,8-dioxo-5,8-dihydroquinoline-2-carboxylic acid;4,6- dihydroxyquinoline-5,8- dione-2 Carboxylic acid;8-hydroxy-4,5,6-trioxo-1H-quinoline-2-carboxylic acid

5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID Basic Attributes

235.151

235.01200

DTXSID00605478

2933499090

Characteristics

124.79000

0.30630

5,8-DIHYDRO-4,6-DIHYDROXY-5,8-DIOXO-2-QUINOLINECARBOXYLIC ACID Use and Manufacturing

Methods of Manufacturing

Heat condensation with 2, 4, 5-trimethoxyaniline and diethyl ketone diacid to produce diethyl 2, 4, 5-trimethoxy aniline ketal. The latter is cyclized under high temperature heating to obtain ethyl 4-hydroxy-5, 6, 8-trimethoxyquinoline-2-carboxylate, which is then subjected to acid hydrolysis to obtain 4, 5, 6, 8-tetrahydroxyquinoline- 2-Carboxylic acid hydrobromide is then oxidized with potassium ferricyanide under alkaline conditions to obtain the product.

Uses

Intermediate stop in the white.

Computed Properties

Molecular Weight:235.15
XLogP3:-1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:235.01168688
Monoisotopic Mass:235.01168688
Topological Polar Surface Area:121
Heavy Atom Count:17
Complexity:578
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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