EC-17

Folate Fitc has been used in trials studying the diagnostic of Ovarian Cancer.|Folate-FITC is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity.

Molecular Weight:872.9
XLogP3:1.3
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:13
Exact Mass:872.23365856
Monoisotopic Mass:872.23365856
Topological Polar Surface Area:338
Heavy Atom Count:63
Complexity:1760
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes