Ethylamine
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Ethylamine
structure -
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CAS No:
75-04-7
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Formula:
C2H7N
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Chemical Name:
Ethylamine
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Synonyms:
1-Aminoethane;ETHYLAMINE ANHYDROUS, PRESSURE TIN WITH 250 ML (NET ~170 G);ETHYLAMINE ANHYDROUS, CYLINDER WITH 2 L (NET ~1 KG);ETHYLAMINE, 2.0M SOLUTION IN METHYL ALCO HOL;ETHYLAMINE, 2.0M SOLUTION IN TETRAHYDRO- FURAN;ETHYLAMINE ANHYDROUS, CYLINDER WITH 27 L (NET ~15 KG);ETHYLAMINE ANHYDROUS, PRESSURE TIN WITH 100 ML;ETHYLAMINE, 70 WT. % SOLUTION IN WATER
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CAS No:
Description
Ethylamine (C2H5NH2), also known by its chemical formula C_2H_5NH_2, is a colorless, volatile liquid or gas that possesses a strong, ammonia-like odor. This compound is categorized as a primary amine, which means that it has a nitrogen atom bonded to one carbon atom and two hydrogen atoms. Ethylamine is highly soluble in various solvents, including water, alcohol, and ether, making it a versatile substance in chemical reactions and applications. Its solubility in these mediums allows ethylamine to easily mix and react with other substances, which is a key property for its use in industrial and laboratory settings.
Ethylamine is a colorless gas or water-whiteliquid (below 17℃) with a strong, ammonia-like odor.Shipped as a liquefied compressed gas. Molecularweight = 45.10; Specific gravity (H2O:1) = 0.69 (liquid);Boiling point = 16.7℃; Freezing/Melting point = - 81℃;Vapor pressure = 847 mmHg at 20℃; Flash point≤ - 18℃; Autoignition temperature = 385℃. Explosivelimits: LEL = 3.5%; UEL = 14.0%. Hazard Identification(based on NFPA-704 M Rating System): Health 3,Flammability 4, Reactivity 0. Soluble in water
Colorless to yellow gas; ammonia fishy aroma.
Ethylamine is a colorless gas or water-white liquid (below 17℃). Strong, ammonia-like odor. Shipped as a liquefied compressed gas.
Ethylamine is a very strong base and its complete solubility in water makes it ideal as an intermediate in many chemical syntheses. As with other primary amines, its chemical reactivity is dictated by the unshared pair of electrons on the nitrogen and its most characteristic reaction is with acids to form salts.
Ethylamine Basic Attributes
45.08
45.08
505933
200-834-7
TSCA listed
Colorless to Light yellow to Light orange
29211990
Characteristics
26.02000
Colorless liquid or gas with a strong ammonia-like odor. An experimentally determined odor threshold concentration of 21 ppbvwas reported by Leonardos et al. (1969). Experimentally determined detection and recognition odor threshold concentrations were 500 μg/m3(270 ppbv) and 1.5 mg/m3(810 ppbv), respectively (Hellman and Small, 1974).
Reactivity with Water No reaction; Reactivity with Common Materials: Will strip and dissolve paint; dissolves most plastic materials; can cause swelling of rubber by absorption. The reactions are not hazardous; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
0.66530
Ethylamine appears as a colorless liquid or a gas (boiling point 62°F) with an odor of ammonia. Flash point less than 0°F. Density of liquid 5.7 lb / gal. Corrosive to the skin and eyes. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Exposure of the closed container to intense heat may cause it to rupture violently and rocket.
0.81 g/mL at 20 °C
-81 °C(lit.)
17 °C
-17ºC
n20/D1.384
miscible
2-8ºC
874 mm Hg ( 20 °C)
1.56 (15 °C, vs air)
The effects of ethylamine appear due primarily to its corrosive action at all points of contact with the body.
Flammable Gas
vol% in air: 3.54
Pungent; strong ammoniacal.
>14 (20°C in H2O)
10.7(at 25℃)
1.23(x 10-5atmm3/mol at 25 °C) (Christie and Crisp, 1967)
Highly flammable. Water soluble.
Sensitive to heat. Reacts vigorously with oxidizing agents. Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Incompatible with cellulose nitrate. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. Also incompatible with oxidizing agents. A chemical base. Neutralizes acids to form salts plus water in an exothermic reaction Dissolves most paints, plastics and rubber .
721 °F
2-8°C
Safety Information
II
3
UN 1036/2270
1
F+,Xi,T,F,Xn
26-29-16-45-36/37-7-36/37/39
KH2100000
Xi
Ethylamine should be stored in a flammable-liquids storage room or cabinet. It shouldbe stored away from oxidizing materials andsources of ignition. It is shipped in steelcylinders or drums.
Stable. Highly flammable. Incompatible with oxidizing agents, alkali metals, alkaline earth metals, acids, many reactive organic and inorganic compounds. Reacts with or disssolves most types of paint, plastic and rubber.
P210, P261, P264, P271, P280, P304+P340, P305+P351+P338, P312, P337+P313, P377, P381, P403, P403+P233, P405, P501
Strong irritant. Flammable, dangerous fire risk, flammable limits in air 3.5–14%.
The aqueous solution is a strong base. May form explosive mixture with air. Reacts violently with strong acids; strong oxidizers; cellulose nitrate; and organic compounds; causing fire and explosion hazard. Also incompatible with organic anhydrides; isocyanates, vinyl acetate; acrylates, substituted allyls; alkylene oxides; epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacksnonferrous metals: aluminum, copper, lead, tin, zinc, and alloys; some plastics, rubber, and coatings.
UN 2270 3/PG II (ETHYLAMINE, AQUEOUS SOLUTION with not less than 50 % but not more than 70 % ethylamine)
P210; P280; P301 + P312 + P330; P305 + P351 + P338; P370 + P378; P403 + P235
Drug Information
Ethylamine is a severe irritant to the eyes,skin, and respiratory system. The pure liquidor its highly concentrated solution can causecorneal damage upon contact with eyes. Skincontact can result in necrotic skin burns.Rabbits exposed to 100 ppm ethylaminefor 7 h/day, 5 days/week for 6 weeks mani fested irritation of cornea and lung, and liverand kidney damage (ACGIH 1986). A 4-hourexposure to 3000 ppm was lethal to rats. Theacute oral and dermal toxicity of this com pound was moderate in test animals.LD50 value, oral (rats): 400 mg/kgLD50 value, skin (rabbits): 390 mg/kg.
Ethylamine Use and Manufacturing
Triazine herbicides used in the production of pesticides include atrazine and simazine ([122-34-9]). The production process of these two herbicides using cyanuric chloride as raw material also has similarities. Ethylamine is also used in the production of dyes, rubber accelerators, surfactants, antioxidants, ion exchange resins, aircraft fuels, solvents, detergents, lubricants, metallurgical dressing agents, and cosmetics and pharmaceuticals.
In resin chemistry; stabilizer for rubber latex; intermediate for dyestuffs, pharmaceuticals; in oil refining
Ethylamine is used in the manufacture ofdyes and resins, as a stabilizer for rubberlatex, and in organic synthesis.
The methods employed for the production of ethylamine are similar to those used for the methylamines. Differences involve the alcohol used and its ratio to other reactants. The most common method involves continuously passing ammonia and ethanol over a catalyst in a gas-solid heterogenous reaction. The temperature is maintained at 300-500°C at 790-3550 kPa and the catalyst can be alumina, silica, titania, or tungstic oxides. As this procedure produces a mixture of water, alcohol, ammonia, and various amines, the amines of interest are continuously separated by distillations and extractions. The amine can be produced from ethyl chloride and alcoholic ammonia under heat and pressure or by hydrogenation of nitroethane (HSDB 1989). Alternatively ammonia, ethanol and hydrogen over a dehydrogenation catalyst are passed continuously over a catalyst (supported metallic silver, nickel, or copper) in a gas-solid heterogenous reaction. The reaction is run at 130-250°C at 790-3550 kPa and also produces a mixture of amines. Ethylamine can also be produced using a similar procedure which employs ammonia and an aldehyde or ketone and hydrogen over a hydrogenation catalyst under the same conditions. However, this method is more expensive and is therefore not commonly used, except in special cases (Schweizer et al 1978).Ethylamine also is a normal constituent of biological systems and is present in the urine of animals and man (Beard and Noe 1981). The amine occurs widely in the environment as a decomposition product of amino acids. It is formed, therefore, in sewage during the decomposition of plant and animal wastes and is also found in a variety of foods such as cheese, herring, spinach and freeze-dried coffee (HSDB 1989; Lin et al 1983,1984). It is also a constituent of tobacco smoke and has been detected in various surface waters at concentrations ranging between 1 and 37 p.p.m. Ethylamine also has been found in finished drinking water (Neurath et al 1977; Scheiman et al 1974). As with other alkylamines, ethylamine can be nitrosated to form the toxic product, 7V-nitrosoethylamine (Hussain et al 1974).
Analysis Methods
| Name | Column Shape | Active Phase(℃) | Retention index | Temperature Control | Method | Comments | Reference |
|---|---|---|---|---|---|---|---|
| Kovats' RI, non-polar column, isothermal | Packed | PMS-100 | 390. | 130. | isothermal | He, Celite 545 (44-60 mesh); Column length: 3. m | Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63. |
| Kovats' RI, non-polar column, isothermal | Packed | PMS-100 | 379. | 150. | isothermal | He, Celite 545 (44-60 mesh); Column length: 3. m | Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63. |
| Kovats' RI, non-polar column, isothermal | Packed | PMS-100 | 370. | 180. | isothermal | He, Celite 545 (44-60 mesh); Column length: 3. m | Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63. |
| Kovats' RI, non-polar column, isothermal | Packed | Apiezon L | 458. | 100. | isothermal | Golovnya, R.V.Zhuravleva, I.L.Gas Chromatographic Method of Identification of n-Aliphatic Amines Through the Use of Donor-Acceptor Interaction with PhosphateChromatographia1973, 6, 12, 508-513. | |
| Kovats' RI, non-polar column, isothermal | Packed | Apiezon L | 441. | 130. | isothermal | Teflon-Haloport; Column length: 2.26 m | Landault, C.Guiochon, G.Separation des amines par chromatographie gaz-liquide en utilisant le teflon comme supportJ. Chromatogr.1964, 13, 327-336. |
Computed Properties
Molecular Weight:45.08
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:45.057849228
Monoisotopic Mass:45.057849228
Topological Polar Surface Area:26
Heavy Atom Count:3
Complexity:2.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Price Analysis
- Data: 2026-07-23
- Price: 7700.00Yuan/mt
- Change: 0
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