Erythromycin A Oxime
-
Erythromycin A Oxime
structure -
-
CAS No:
111321-02-9
-
Formula:
C37H68N2O13
-
Chemical Name:
Erythromycin A Oxime
-
Synonyms:
(9E)-ErythroMycin A OxiMe;Erythromycin A Oxime;(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9;Azithromycin Impurity S ((9E)-Erythromycin A Oxime);(9E)-Erythromycin A Oxime Roxithromycin EP Impurity C;Roxithromycin EP Impurity C (Erythromycin Impurity J);Erythromycin Impurity J;(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2R,3R,4S,6R)- 4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2- yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5- hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl) oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyl oxacyclotetradecan-2-one
-
CAS No:
Description
Off-White Solid
(9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin .
Characteristics
209.43000
2.04670
1.28±0.1 g/cm3(Predicted)
156-166 °C
841.0±65.0 °C(Predicted)
11.96±0.70(Predicted)
Refrigerator
Erythromycin A Oxime Use and Manufacturing
Erythromycin A 9-oxime is a semi-synthetic analogue of erythromycin prepared as means of overcoming acid lability and improving oral absorption of erythromycin A while retaining comparable antibacterial potency. Although not developed as a commercial product, erythromycin oxime was pivotal in the development of the ring expanded aza-erythromycins (e.g. azithromycin) and the oxime ethers (e.g. roxithromycin).
Intermediate of Azithromycin. Antibacterial agent.
(9E)-Erythromycin A Oxime is a metabolite of Roxithromycin (R700850) in humans. It has anti-Helicobacter pylori activity
Computed Properties
Molecular Weight:748.9
XLogP3:3
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:7
Exact Mass:748.47214023
Monoisotopic Mass:748.47214023
Topological Polar Surface Area:209
Heavy Atom Count:52
Complexity:1210
Undefined Atom Stereocenter Count:18
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Erythromycin A Oxime
-
![China]()
CN
YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
Learn More Other Chemicals
-
Cyclohexanone, 2-hydroxy-2-methoxy-, oxime (9CI)
781559-58-8
-
3-(2,4-DICHLOROPHENYL)-3-OXO-2-(2-PHENYLHYDRAZONO)PROPANAL OXIME
339279-73-1
-
2,4-DICHLOROACETOPHENONE OXIME
71516-67-1
-
2,4-DICHLORO-1,3-THIAZOLE-5-CARBOXALDEHYDE OXIME Formula
666257-91-6
-
Megalomicin A bis(potassium dihydrogen phosphate) Formula
23319-48-4
-
3-(4-BROMOPHENYL)-2-[2-(3,5-DICHLOROPHENYL)HYDRAZONO]-3-OXOPROPANAL OXIME Formula
339279-66-2
-
(4-BROMOPHENYL)(7-METHOXY-1-BENZOFURAN-2-YL)METHANONE OXIME Structure
477848-44-5
-
2-Thiophenecarboxaldehyde, oxime Structure
29683-84-9
-
What is (2,4-DICHLOROPHENYL)(7-METHOXY-1-BENZOFURAN-2-YL)METHANONE OXIME
477848-46-7
-
What is [3-(2,6-DICHLOROPHENYL)-ISOTHIAZOL-4-YL]-CARBAMOYL 2,6-DICHLOROBENZALDEHYDE OXIME
832113-70-9