Ethyl 4,6,6-trichloro-3,3-dimethyl-5-hexenoate

The preparation method is to add 1, 1, 1-trichloro-4-methyl-pentene [3] alcohol-[2] into the reactor, then add triethyl orthoacetate and the catalyst isobutyric acid, stir, heat, With nitrogen gas, the temperature is uniformly heated from 110°C to 150°C, about 12h, with distillate (mainly toluene, ethanol, ethyl acetate, etc.) distilled out, reacted at 150-155°C for 7-8h, and gas chromatography Control the end point, end the reaction, cool, distill off the front fraction at a pressure of 0.08 MPa, and the rest is 3, 3-dimethyl-4, 6, 6-trichlorohexene [5] ethyl ester.

3,3-Dimethyl-4,6,6-trichlorohexene[5] acid ethyl ester is an intermediate for the preparation of permethrin by the Sagami-Kualai method.

Molecular Weight:273.6
XLogP3:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:272.013763
Monoisotopic Mass:272.013763
Topological Polar Surface Area:26.3
Heavy Atom Count:15
Complexity:245
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes