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ENDOMORPHIN-1

ENDOMORPHIN-1 structure

CAS No:
189388-22-5
Formula:
C34H38N6O5
Chemical Name:
ENDOMORPHIN-1
Synonyms:
L-Tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide;L-Phenylalaninamide,L-tyrosyl-L-prolyl-L-tryptophyl-;H-TYR-PRO-TRP-PHE-NH2;ENDOMORPHIN-1;ENDOMORPHIN-1 (HUMAN, BOVINE);TYR-PRO-TRP-PHE-NH2;YPWF-NH2;(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-2-(1H-indol-3-yl)ethyl]pyrrolidine-2-carboxamide
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Endomorphin 1, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.

Solid

L-Phenylalaninamide, L-tyrosyl-L-prolyl-L-tryptophyl- is an oligopeptide.

ENDOMORPHIN-1 Basic Attributes

Molecular Weight：

610.7

Exact Mass：

610.29000

DSSTox ID：

DTXSID10415505

Characteristics

PSA：

184

XLogP3：

3.79490

Appearance：

White to off-white Solid

Density：

1.343±0.06 g/cm3(Predicted)

Melting Point：

144-146℃

Boiling Point：

1052.8±65.0 °C(Predicted)

Flash Point：

590.5ºC

Refractive Index：

1.671

Storage Conditions：

−20°C

Safety Information

wgk germany：

RTECS Number：

SQ7316800

Drug Information

MeSH：

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)

MeSH Entry Terms：

(Dmt1)endomorphin-1

Computed Properties

Molecular Weight:610.7
XLogP3:2.4
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:610.29036833
Monoisotopic Mass:610.29036833
Topological Polar Surface Area:184
Heavy Atom Count:45
Complexity:1030
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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High Quality Pure 99% TYR-PRO-TRP-PHE-NH2 Endomorphi-1 Raw Powder CAS 189388-22-5

Unit Price: $300-350 /G FOB

CAS No.: 189388-22-5

Grade: Pharmaceutical Grade

Content: 98%

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