Mivobulin isethionate
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Mivobulin isethionate
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CAS No:
126268-81-3
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Formula:
C17H19N5O2.C2H6O4S
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Chemical Name:
Mivobulin isethionate
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Synonyms:
canertinib dihydrochloride;CI 980;CI-980;PD 183805;PD-183805;PD183805;Mivobulin isethionate;UNII-8J08028R66;8J08028R66
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CAS No:
Description
Mivobulin Isethionate is the isethionate salt of mivobulin, a synthetic colchicine analogue with potential antineoplastic activity. Mivobulin isethionate binds to tubulin, thereby inhibiting microtubule polymerization and mitosis.
Drug Information
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate. (See all compounds classified as Anesthetics, Local.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)|Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)
canertinib dihydrochloride
Computed Properties
Molecular Weight:451.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:451.15255471
Monoisotopic Mass:451.15255471
Topological Polar Surface Area:185
Heavy Atom Count:31
Complexity:595
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Learn More Other Chemicals
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Mivobulin
122332-18-7
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6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZINE-3,5-DIAMINE ISETHIONATE
113170-86-8
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Hydroxystilbamidine isethionate
533-22-2
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Potassium isethionate Formula
1561-99-5
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Propamidine isethionate Formula
140-63-6
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PD0332991 Isethionate Formula
827022-33-3
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Dibromopropamidine isethionate Structure
614-87-9
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Pentamidine isethionate Structure
140-64-7
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What is Ammonium isethionate
57267-78-4
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What is Sodium isethionate
1562-00-1