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Succinimidyl 3-maleimidopropionate

Succinimidyl 3-maleimidopropionate structure

CAS No:
55750-62-4
Formula:
C11H10N2O6
Chemical Name:
Succinimidyl 3-maleimidopropionate
Synonyms:
1H-Pyrrole-1-propanoic acid,2,5-dihydro-2,5-dioxo-,2,5-dioxo-1-pyrrolidinyl ester;1H-Pyrrole-2,5-dione,1-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-;3-Maleimidopropionic acid hydroxysuccinimide ester;N-Succinimidyl 3-(N-maleimido)propionate;N-Succinimidyl 3-maleimidopropionate;β-Maleimidopropionic acid N-hydroxysuccinimide ester;3-Maleimidopropionic acid N-hydroxysuccinimide ester;BMPS;BMPS (crosslinking agent);3-(2,5-Dioxo-2,5-dihydropyrrol-1-yl)propionic acid 2,5-dioxopyrrolidiny-1-yl ester;Succinimidyl 3-maleimidopropanoate;3-Maleimidopropionic acid N-succinimidyl ester;Succinimidyl 3-maleimidopropionate;2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-lH-pyrrol-1-yl)propanoate;(2,5-Dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate;2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
Categories:
Chemical Reagents > Organic Reagents

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Description

BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Succinimidyl 3-maleimidopropionate Basic Attributes

Molecular Weight：

266.21

Exact Mass：

266.21

EC Number：

1533716-785-6

DSSTox ID：

DTXSID30404976

HScode：

2925190090

Characteristics

PSA：

101

XLogP3：

-1.6

Density：

1.55g/cm3

Melting Point：

158-161 °C @ Solvent: Dichloromethane, Hexane

Boiling Point：

448.8°C at 760 mmHg

Flash Point：

225.2ºC

Refractive Index：

1.605

Water Solubility：

Insoluble in water.

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

26-36/37/39-24/25

Marks：

Precautionary statement(s)：

P261

Hazard Statements：

H335

GHS Classification：

|Warning|H315 (13.33%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Succinimidyl 3-maleimidopropionate Use and Manufacturing

A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent.Also used in immunodiagnostics.Spacer Arm: 6.9 Angstroms

Computed Properties

Molecular Weight:266.21
XLogP3:-1.6
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:266.05388604
Monoisotopic Mass:266.05388604
Topological Polar Surface Area:101
Heavy Atom Count:19
Complexity:475
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 55750-62-4

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Guide of Succinimidyl 3-maleimidopropionate

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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Succinimidyl 3-maleimidopropionate

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