5-Iodoisatin
-
5-Iodoisatin
structure -
-
CAS No:
20780-76-1
-
Formula:
C8H4INO2
-
Chemical Name:
5-Iodoisatin
-
Synonyms:
1H-Indole-2,3-dione,5-iodo-;Indole-2,3-dione,5-iodo-;Isatin,5-iodo-;5-Iodo-1H-indole-2,3-dione;5-Iodoisatin;NSC 92515;5-Iodoindoline-2,3-dione
-
CAS No:
Characteristics
46.2
1.56400
red solid
2.1±0.1 g/cm3
264-265 °C @ Solvent: Ethanol, Acetic acid
1.704
soluble acetone, acetic acid, ethanol. Insoluble in water.
Safety Information
LIGHT SENSITIVE
NONH for all modes of transport
3
22-36/37/38-43
26-36
Xn,Xi
Irritant
P261-P280-P305 + P351 + P338
H302-H315-H317-H319-H335
|Warning|H302 (97.56%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 41 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
5-Iodoisatin Use and Manufacturing
Derived from the reaction of indolequinone and iodine chloride. Mix indolequinone with absolute ethanol and glacial acetic acid, and heat to reflux until fully dissolved. When the temperature was raised to 90°C, iodine monochloride was added dropwise under stirring. After the addition, the temperature was maintained at 85-90°C, and the reaction was continued for 70 minutes. Cool and filter to obtain red granular crystals. Wash with alcohol to neutrality and dry (a small amount of crystals can be obtained after the mother liquor recovers the solvent). Get the finished product. The yield is over 80%.
Used in the synthesis of organic iodide.