Diisopropyl ether

102.17500

102.17

203-560-6

DO7Y998826

0906

1159

DTXSID4021890

Colorless volatile liquid|Colorless liquid.|Colorless liquid

2909199090

9.23000

1.8198

Colourless liquid

0.7258 g/cm³ @ Temp: 20 °C

-86.8 °C

68.5 °C

−29 °F

n20/D 1.367(lit.)

H2O: 9 g/L (20 ºC)

Storage Room low temperature ventilation drying ,Separate storage and transportation with oxidants and acids

152mmHg at 25°C

3.5 (vs air)

Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.

vol% in air: 1.4.9

Sweet, slightly sharp, pungent like camphor and ethyl ether

1.02e-11 cm3/molecule*sec

0.00 atm-m3/mole

pKa = -4.30 (conjugate acid)

1 PPM= 4.128 MG/CU M; 1 MG/L= 240 PPM|Ratio of specific heats of vapor (gas): 1.0590; latent heat of vaporization: 131 BTU/lb= 73 cal/g= 3.1X10+5 J/kg|Azeotrope 95.5 wt% at 62.2 °C|Readily forms peroxides when exposed to oxygen unless stabilized with inhibitors such as hydroquinone.

Highly flammable. Slightly soluble in water. Form explosive peroxide in storage. A flask of diisopropyl ether was heated on a steam bath with gentle shaking when an explosion occurred. In a second instance, an explosion occurred after practically all the ether had been distilled, [MCA Guide for Safety(1972)].

Ethers

Highly Flammable

Ethers, such as DIISOPROPYL ETHER, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert. Mixing diisopropyl ether in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, nitric acid, [NFPA 1991].

Isopropyl ether|A: Compounds that form explosive levels of peroxides without concentration|Large amounts of peroxides found in new commerically available containers|Kelly|A long history of very violent explosions, including fatal incidents when bottles were opened. See Bretherick's for individual accounts.|Anon., Chem. Eng. News, 1942, 20, 1458

830 °F (USCG, 1999)|830 °F (443 °C)|443 °C

-16,900 BTU/lb= -9,390 cal/g= -393X10+5 J/kg

9.20 eV

LOWER 1.4%, UPPER 7.9%|Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.

The vapour is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated.

7,777.3 gcal/gmole

Critical temp= 226.9 °C; Critical pressure= 28.4 atm

II

3

UN 1159 3/PG 2

1

R11; R19; R66; R67

S9-S16-S29-S33

TZ5425000

F

Fireproof. Cool. Keep in the dark. Keep in a well-ventilated room. Store only if stabilized.

Keeping ethers from becoming anhydrous plus the addition of antioxidants will help reduce this explosion hazard.

P210-P261-P273

H225-H336-H412

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|Isopropylether may be disposed of by atomizing in a suitable combustion chamber.|Isopropyl ether is a waste chemical stream constituent which may be subjected to ultimate disposal by controlled incineration.|The following wastewater treatment technologies have been investigated for isopropyl ether: Concentration process: Biological treatment.|For more Disposal Methods (Complete) data for ISOPROPYL ETHER (8 total), please visit the HSDB record page.

Mixing diisopropyl ether and chlorosulfonic acid in a closed container caused the temp and pressure to incr. Mixing diisopropyl ether and 70% nitric acid in a closed container caused the temp and pressure to increase.|The short alkyl-chain ether hydroperoxides ... are dangerous and ... all ethers should be tested and separated from peroxidic products before distillation or evaporation. /Short alkyl-chain ethers/|Isopropyl ether autooxidizes to form peroxides and hydroperoxides at 20 °C with UV radiation or in the presence of a photosensitizer, eg, benzophenone|Mixtures of propionyl chloride with diisopropyl ether are very unstable. The exothermic reaction giving isopropyl propionate and isopropyl chloride can proceed spontaneously. This reaction is catalyzed by low concn of zinc tetrachloride (4 ppm) or somewhat less effectively by iron trichloride (40 ppm). In this way pressure may build up in closed vessels and explode. Premixing of ethers and acid chlorides should be avoided.|For more Hazardous Reactivities and Incompatibilities (Complete) data for ISOPROPYL ETHER (6 total), please visit the HSDB record page.

Behavior in Fire: Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back. Containers may explode when heated. (USCG, 1999)|Highly flammable. Vapour/air mixtures are explosive.|Flammable - 3rd degree, Reactive - 1st degree

|Danger|H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P271, P273, P280, P303+P361+P353, P304+P340, P312, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 396 companies from 20 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H225: Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P312, P370+P378, P403+P233, P403+P235, P405, and P501|P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P281, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P309+P311, P312, P332+P313, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Skin: Wear appropriate personal protective clothing to prevent skin contact. Eyes: Wear appropriate eye protection to prevent eye contact. Wash skin: The worker should immediately wash the skin when it becomes contaminated. Remove: Work clothing that becomes wet should be immediately removed due to its flammability hazard(i.e. for liquids with flash point Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. (NIOSH, 2016)|WEAR FULL PROTECTIVE CLOTHING & POSITIVE PRESSURE SELF-CONTAINED BREATHING APPARATUS.|Wear appropriate personal protective clothing to prevent skin contact.|Wear appropriate eye protection to prevent eye contact.|Recommendations for respirator selection. Max concn for use: 1400 ppm. Respirator Class(es): Any chemical cartridge respirator with organic vapor cartridge(s). May require eye protection. Any powered, air-purifying respirator with organic vapor cartridge(s). May require eye protection. Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister. Any supplied-air respirator. May require eye protection. Any self-contained breathing apparatus with a full facepiece.|For more Personal Protective Equipment (PPE) (Complete) data for ISOPROPYL ETHER (6 total), please visit the HSDB record page.|(See protection codes)

FLAMMABLE LIQUID.|ONLY ELECTRICAL EQUIPMENT OF EXPLOSION-PROOF TYPE (GROUP C CLASSIFICATION) IS PERMITTED TO BE OPERATED IN ETHER AREAS. ETHER SHOULD NOT BE STORED NEAR POWERFUL OXIDIZERS OR IN AREAS OF HIGH FIRE HAZARD. /ETHERS/

UNSTABILIZED MATERIAL READILY FORMS PEROXIDES & MAY EXPLODE ON SHAKING.|Diisopropyl ether & air form highly explosive peroxides. A flask of diisopropyl ether was being heated on a steam bath with gentle shaking when an explosion occurred. In a second instance, an explosion occurred after practically all the ether had been distilled.|lel: 1.4%; uel: 7.9%|A very dangerous fire hazard and severe explosion hazard when exposed to heat, flame, sparks, or oxidizers. Under some conditions shock will explode it. Dangerous; on exposure to air it rapidly forms very sensitive, explosive peroxides that precipitate as crystals.|Explosive limits , vol% in air: 1.4-7.9

Alcohol foam, CO2, foam, dry chemical.

VAPORS ARE HEAVIER THAN AIR & MAY TRAVEL TO A SOURCE OF IGNITION & FLASH BACK. LIQUID FLOATS ON WATER & MAY TRAVEL TO A SOURCE OF IGNITION & SPREAD FIRE. ETHER TENDS TO FORM UNSTABLE, EXPLOSIVE PEROXIDES ON STANDING.

1. Remove all ignition sources. 2. Ventilate area of spill or leak. 3. For small quantities, absorb on paper towels. Evaporate in a safe place (such as fume hood). Allow sufficient time for evaporating vapors to completely clear the hood ductwork. Burn the paper in a suitable location away from combustible materials. Large quantities can be reclaimed or collected and atomized in a suitable combustion chamber.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|TEST ALL ISOPROPYL ETHER FOR PEROXIDES BEFORE USING & DESTROY PEROXIDES WITH SODIUM SULFITE SOLN.|The worker should immediately wash the skin when it becomes contaminated.|Work clothing that becomes wet should be immediately removed due to its flammability hazard.

/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.|/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Health: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.|/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.|For more DOT Emergency Guidelines (Complete) data for ISOPROPYL ETHER (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

At 800 ppm for five minutes most subjects reported irritation of the eyes and nose.|Mildly toxic by ingestion, inhalation, and skin contact. A skin irritant.

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 500 ppm (2100 mg/cu m).

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 500 ppm (2100 mg/cu m).

Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking and spilled liquid in sealable metal containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Fireproof. Cool. Keep in the dark. Keep in a well-ventilated room. Store only if stabilized.

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.

The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. Exposure above the OEL could cause lowering of consciousness.

Repeated or prolonged contact with skin may cause dermatitis.

NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).

Use ventilation, local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles.

| 1 - Materials that, under emergency conditions, can cause significant irritation.| 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions.| 1 - Materials that in themselves are normally stable but that can become unstable at elevated temperatures and pressures.| 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury.

Isopropyl ether has been detected in 10 out of 63 samples of industrial effluents collected from a wide variety of industries across the USA (dates not reported)(1). Six of the positive samples contained <10 ug/L isopropyl ether, 3 samples contained 10-100 ug/L and 1 sample contained >100 ug/L(1). Samples of landfill gas from an unspecified landfill which had for more than 15 months accepted municipal and industrial solid wastes and unspecified liquid wastes contained 220 mg/cu m isopropyl ether(2).

Isopropyl ether was identified, but not quantified, at 4 of 7 sites in the Kanawha Valley, WV, sampled in Sept 1977(1).

Isopropyl ether's production and use as an extraction agent and as a solvent in paints/stain removers(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 160(SRC), determined from a log Kow of 1.52(2) and a regression-derived equation(3), indicates that isopropyl ether is expected to have high mobility in soil(SRC). Volatilization of isopropyl ether from moist soil surfaces is expected to be important(3,SRC) given an estimated Henry's Law constant of 2.3X10-3 atm-cu m/mole(SRC), calculated from its water solubility(4) and vapor pressure(5). The potential for volatilization of isopropyl ether from dry soil surfaces may exist(SRC) based on a vapor pressure of 149 mm Hg(5). Isopropyl ether is not expected to hydrolyze in soil due to lack of hydrolyzable functional groups(3). Aqueous screening test data from studies using activated sludge or sewage inocula(6,7) suggest that isopropyl ether may be resistant to biodegradation in environmental media(SRC). Many ethers are known to be resistant to biodegradation(8).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 160(SRC), determined from a log Kow of 1.52(2) and a regression-derived equation(3), indicates that isopropyl ether is not expected to adsorb to suspended solids and sediment in water(SRC). Isopropyl ether is expected to volatilize rapidly from water surfaces(3,SRC) based on an estimated Henry's Law constant of 2.3X10-3 atm-cu m/mole(SRC), calculated from its water solubility(4) and vapor pressure(5). Estimated volatilization half-lives for a model river and model lake are 3 hours and 4 days, respectively(3,SRC). Isopropyl ether is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3). Isopropyl ether will not significantly photooxidize via reaction with photochemically produced hydroxyl radicals in the water(6). According to a classification scheme(7), an estimated BCF of 8(3,SRC), from isopropyl ether's log Kow(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Isopropyl ether may be resistant to biodegradation in environmental media based upon screening test data from studies using activated sludge or sewage inocula(8,9,SRC). Many ethers are known to be resistant to biodegradation(10).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), isopropyl ether, which has a vapor pressure of 149 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase isopropyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 21 hours(3,SRC). The half-life for the reaction of isopropyl ether with nitrate radicals is estimated as 9 seconds(4,SRC). Direct photolysis will not be an important removal process since aliphatic ethers do not absorb light at wavelengths >290 nm(5).

The rate constant for the vapor phase reactions of isopropyl ether with photochemically produced hydroxyl radicals has been measured to be 1.85X10-11 cu cm/molecule-sec at 25 °C(1) which corresponds to a half-life of 21 hours at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm (SRC). The rate constant for the vapor phase reactions of isopropyl ether with night-time nitrate has been determined to be 5.18X10-15 cu cm/molecule-sec at 25 °C(2), which corresponds to a half-life of 9 seconds at an atmospheric concn of 2X10+13 nitrate molecules per cu cm(SRC). Reaction of isopropyl ether with photochemically produced alkoxy radicals in water is not expected to be an important fate process(3). Direct photolysis will not be an important removal process since aliphatic ethers do not absorb light at wavelengths >290 nm(4). Isopropyl ether is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(5).

An estimated BCF of 8 was calculated for isopropyl ether(SRC), using a log Kow of 1.52(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of isopropyl ether is estimated as approximately 160(SRC), using a log Kow of 1.52(1) and a regression-derived equation(2,SRC). According to a classification scheme(3), this estimated Koc value suggests that isopropyl ether is expected to have high mobility in soil(SRC).

The Henry's Law constant for isopropyl ether is estimated as 2.3X10-3 atm-cu m/mole(SRC) from its experimental values for vapor pressure, 149 mm Hg(2), and water solubility, 8,800 mg/l(1). This Henry's Law constant indicates that isopropyl ether is expected to volatilize rapidly from water surfaces(3,SRC). Based on this Henry's Law constant, the estimated volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is approximately 3 hours(3,SRC). The estimated volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is approximately 4 days(3,SRC). Isopropyl ether's Henry's Law constant(1,2,SRC) indicates that rapid volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of isopropyl ether from dry soil surfaces may exist(SRC) based on a vapor pressure of 149 mm Hg(1).

Isopropyl ether was detected in 1 of 14 samples of treated drinking water in England in 1978 and 1979; the drinking water with isopropyl ether was derived from river water(1).|GROUNDWATER: Isopropyl ether has been found in groundwater in the U.S. from unspecified sites at a concn range of 20-34 ppb(1). Isopropyl ether has been detected at concn up to 160 ppb in the Old Bridge aquifer under an industrial plant in South Brunswick Township, NJ (no sampling dates specified)(2). A contamination abatement system installed at this aquifer, including 7 extraction wells and a water treatment facility, reduced the isopropyl ether concn by an estimated 92%(2). It was detected at concn ranging from 13-128 ug/L in 12 of 12 samples of groundwater taken from between March 1985 and Feb 1986 from an aquifer near Dijon, France which was contaminated by a nearby industrial area(3). Isopropyl ether was detected in groundwater collected from wellfields across the Netherlands, concn unknown(4).|SURFACE WATER: Isopropyl ether has been found in the following Lake Michigan basin locations: Chicago Sanitary and Ship Channel, 1 ug/L(1). Isopropyl ether was found at a concn of 1 ppb in samples of surface water from 2 of 204 sites near heavily industrialized areas across the U.S sampled between Aug 1975 and Sept 1976(2).

The most probable routes of general population exposure to ether are via handling of paints and stain removers, inhalation of contaminated air(2,SRC) and ingestion of contaminated drinking water(1,SRC). Exposure through dermal contact may occur in occupational settings(SRC). Inhalation and dermal exposure will be expected to be highest in workplaces where isopropyl ether is made and used(SRC).|NIOSH (NOES Survey 1981-1983) has statistically estimated that 3,253 workers (1,126 of these are female) are exposed to isopropyl ether in the USA(1).

... ISOPROPYL ETHER IS RAPIDLY ABSORBED BY BLOOD FROM LUNGS OR GI TRACT. ... IT IS PROBABLE THAT MAJOR PORTION OF DOSE IS ELIMINATED THROUGH LUNGS AFTER CESSATION OF EXPOSURE ... .

COMMERCIAL VARIETY MAY CONTAIN APPROX 3% OF ISOPROPYL ALC, LESS THAN 0.01% OF SULFUR & LESS THAN 0.04% OF PEROXIDE.|The dehydration of isopropyl alcohol with sulfuric acid produces propylene as an impurity in the production of isopropyl ether. The amounts of propylene by-product will vary with type of catalyst and reaction conditions.|Isopropyl ether autooxidizes to form peroxides and hydroperoxides at 20 °C with UV radiation or in the presence of a photosensitizer, eg, benzophenone

Inhalation causes anesthesia, nausea, headache, dizziness, and irritation of the eyes and nose. Contact of liquid with eyes causes only minor injury; repeated contact with skin will remove natural oils and may cause dermatitis. (USCG, 1999)

Eye: If this chemical contacts the eyes, immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical. Skin: If this chemical contacts the skin, promptly wash the contaminated skin with soap and water. If this chemical penetrates the clothing, promptly remove the clothing and wash the skin with soap and water. Get medical attention promptly. Breathing: If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform mouth-to-mouth resuscitation. Keep the affected person warm and at rest. Get medical attention as soon as possible. Swallow: If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2016)|(See procedures)

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Provide a low-stimulus environment. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Treat frostbite by rapid rewarming ... . /Ethers and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: To keep open, "minimal flow rate"/. Use lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ethers and related compounds/

Toxic symptoms similar to ethyl ether.|MILDLY IRRITATING TO SKIN, MUCOUS MEMBRANES. INHALATION OF HIGH CONCENTRATIONS CAUSES /CNS DEPRESSION/, UNCONSCIOUSNESS. DEATH MAY OCCUR DUE TO RESP PARALYSIS. /ETHYL ETHER/|Isopropyl ether has an anesthetic action very much like ethyl ether, but is somewhat more toxic.|Human exposure to 500 ppm over a 15 min period caused no irritation, but irritation of the eyes and nose was noted at 800 ppm for 5 min with some respiratory discomfort. Industrial exposure has caused but few cases of death or serious injury. Repeated skin contact would be expected to cause dermatitis.|... a group of subjects exposed for 15 minutes at 500 ppm did not consider the exposure to be irritating. At a concentration of 300 ppm, however, about one-third of the subjects objected to the unpleasant odor, while at 800 ppm for five minutes most subjects reported irritation of the eyes and nose.

diisopropyl ether

The substance can be absorbed into the body by inhalation of its vapour.|inhalation, ingestion, skin and/or eye contact

irritation eyes, skin, nose; resp discomfort; dermatitis; In Animals: drowsiness, dizziness, unconsciousness, narcosis

Cough. Drowsiness. Sore throat.

Dry skin. Redness.

Redness.

Eyes, skin, respiratory system, central nervous system

Grade: technical.|Purity: 94+%. May contain 0.01% hydroquinone or other inhibitor to prevent peroxide formation|USUALLY CONTAINS P-BENZYLAMINOPHENOL AS STABILIZER.

All other chemical product and preparation manufacturing|Propane, 2,2'-oxybis-: ACTIVE

NIOSH Method 1618. Determination of Isopropyl Ether by Gas Chromatography with Flame Ionization Detection. Solid sorbent tube using coconut shell charcaol. This method is applicable to air samples.|ISOPROPYL ETHER DETERMINED BY TEMP-PROGRAMMED FLAME-IONIZATION GAS CHROMATOGRAPHY USING DINONYL PHTHALATE ON CHROMOSOL W. CARRIER GAS WITH NITROGEN, COLUMN TEMP 110 °C.|NIOSH Method 1610: A gas chromatographic method for the analysis of ethyl ether, consists of a stainless steel column, 1.2 m x 6 mm OD, packed with Porapak Q carrier gas at a flow rate of 30 ml/min, is a NIOSH approved method. A sample s suggested, the column temperature is 175 °C, the injection temperature is 195 °C, and the detection temperature is 250 °C. n limit of 0.01 mg/sample, and a relative This method has a estimated detection limit of 0.01 mg/sample, and a relative standard deviation of 0.024 at 1.8 to 7.1 mg/sample over a working range of 100 to 2500 mg/sample. /Diethyl ether/|EPA Method 1624: An isotope dilution gas chromatography/ mass spectrometry method for the determination of volatile organic compounds in municipal and industrial discharges is described. This method is designed to meet the survey requirements of Effluent Guidelines Division (EGD) and the National Pollution Discharge Elimination System (NPDES). Under the prescribed conditions, unlabeled diethyl ether has a minimum level of 50 ug/l and a mean retention time of 820 sec. The labeled compound has a minimum level of 50 ug/l, a mean retention time of 804 sec, and a characteristic primary m/z of 74/84. /Diethyl ether/|For more Analytic Laboratory Methods (Complete) data for ISOPROPYL ETHER (7 total), please visit the HSDB record page.

Ether in blood or urine is analyzed by direct injection of the specimen into a gas chromatograph equipped with a flame-ionization detector and a molecular sieve column. This method has a sensitivity of 10 mg/l, linearity of 10-200 mg/l, cv of 3-5% within-run, and a relative recovery of 96-100%. /Diethyl ether/

Food Additives -> EXTRACTION_SOLVENT; -> JECFA Functional Classes|Fire Hazards -> Flammable - 3rd degree, Reactive - 1st degree

Food Additives -> EXTRACTION_SOLVENT;