Hederacoside C
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Hederacoside C
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CAS No:
14216-03-6
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Formula:
C59H96O26
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Chemical Name:
Hederacoside C
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Synonyms:
Olean-12-en-28-oic acid,3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-,O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester,(3β,4α)-;Glucopyranose,O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-,1-ester with 3β-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid,β-D-;Akebia saponin PK;Kizuta saponin K12;Hederacoside C;Kalopanaxsaponin B;Pulsatilla saponin F;Saponin K12;Hederoside H1;Koronaroside B;Tauroside St-H2;Akeboside Sth;Glycoside L-H2;Tauroside H2;Saponin PK;Pericarsaponin Pk;Hederasaponin C;Hederagenin 3-O-α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl-28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside;23-Hydroxy-3β-[(O-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl)oxy]olean-12-en-28-oic acid O-α-L-rhamnopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester;3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosylhederagenin 28-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside;Pulchinenoside B5;Clematangoside A;27013-76-9;52038-14-9;52229-78-4;56292-18-3;94021-48-4;103470-80-0;104748-89-2;1002105-94-3;1407838-40-7
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CAS No:
Description
Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects.
Hederacoside C Use and Manufacturing
General procedure: Each compound (10mg) was refluxed with 5N NH4OH in 50% EtOH (10mL) for 15h. After cooling, the reaction mixture was neutralized with 2N HCl and extracted with n-BuOH. The n-BuOH layer was evaporated to dryness to give a residue, which was purified by semipreparative HPLC eluted with MeOH-H2O to yield the prosapogenins (5.5mg for 3a, 4.8mg for 4a and 5.2mg for 5a). Their structures were determined by NMR experiments and ESIMS analyses, and the identification date see Supplementary data.
Solubilizer, bio-availability enhancer in oral suspensions, capsules
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