Saytex BT 93

951.47

951.47

251-118-6

B14GGF3PP8

DTXSID6024626

Off-white powder|Light yellow powder

2925190090

74.76000

8.44

N,n-ethylene-bis(tetrabromophthalimide) is a yellow powder. (NTP, 1992)

2.67

456.0 °C

827.9±65.0 °C at 760 mmHg

454.5±34.3 °C

1.766

<0.1 g/100 mL at 21 ºC

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

2.5X10-22 mm Hg at 25 deg C /Estimated/

Henry's Law constant = 3.6X10-21 atm cu m/mol at 25 °C /Estimated/

Insoluble in water.

Amides and Imides

N,N-ETHYLENE-BIS(TETRABROMOPHTHALIMIDE) may react with strong oxidizers. (NTP, 1992)

3

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

The U.S. high production volume (HPV) chemicals are those which are manufactured in or imported into the United States in amounts equal to or greater than one million pounds per year. Robust Summaries include health effects, ecotoxicity data, and environmental fate information for selected chemicals. EPA/Office of Pollution Prevention and Toxics; High Production Volume (HPV) Challenge Program's Robust Summaries and Test Plans.[Available from, as of November 4, 2004: http://www.epa.gov/hpv/pubs/hpvrstp.htm]

Flash point data for this compound are not available but it is probably non-flammable. (NTP, 1992)

Fires involving this compound should be controlled using a dry chemical, carbon dioxide, foam or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: You should dampen the solid spill material with acetone, then transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the adsorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this chemical under refrigerated temperatures, and keep it away from oxidizing materials. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

LD50 Rat (Sherman-Wistar) oral >7500 mg/kg bw|LC50 Rat inhalation >203 mg/L/1 hr

Ethylene bis(tetrabromophthalimide)'s production and use as a flame retardant in electrical and electronics components, wire and cable insulation, switches, and conductors(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 8.0X10+5(SRC), determined from a structure estimation method(2), indicates that ethylene bis(tetrabromophthalimide) is expected to be immobile in soil(SRC). Volatilization of ethylene bis(tetrabromophthalimide) from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.6X10-21 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Ethylene bis(tetrabromophthalimide) is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.5X10-22 mm Hg(SRC), determined from a fragment constant method(4). A 0% theoretical BOD in 28 days at 25 °C using an activated sludge inoculum and the Japanese MITI test(5) suggests that biodegradation in soil may be slow(SRC).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 8.0X10+5(SRC), determined from a structure estimation method(2), indicates that ethylene bis(tetrabromophthalimide) is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.6X10-21 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 9.5(SRC), from an estimated log Kow of 9.8(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Ethylene bis(tetrabromophthalimide) is expected to undergo hydrolysis in the environment due to the presence of amide groups(SRC). A 0% theoretical BOD in 28 days at 25 °C using an activated sludge inoculum and the Japanese MITI test(8) suggests that biodegradation in water may be slow(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ethylene bis(tetrabromophthalimide), which has an estimated vapor pressure of 2.5X10-22 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase ethylene bis(tetrabromophthalimide) may be removed from the air by wet and dry deposition(SRC).

Ethylene bis(tetrabromophthalimide) is expected to undergo hydrolysis in the environment due to the presence of amide groups; hydrolysis of amides results in the formation of a carboxylic acid and an amine(1).

An estimated BCF of 9 was calculated for ethylene bis(tetrabromophthalimide)(SRC), using an estimated log Kow of 9.8(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low, as would be expected given the size of this molecule and its very low estimated water solublilty of 3.0X10-9 mg/L(4).

Using a structure estimation method based on molecular connectivity indices(1), the Koc for ethylene bis(tetrabromophthalimide) can be estimated to be 8X10+5(SRC). According to a classification scheme(2), this estimated Koc value suggests that ethylene bis(tetrabromophthalimide) is expected to be immobile in soil.

The Henry's Law constant for ethylene bis(tetrabromophthalimide) is estimated as 3.6X10-21 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that ethylene bis(tetrabromophthalimide is expected to be essentially nonvolatile from water surfaces(2). Ethylene bis(tetrabromophthalimide)'s Henry's Law constant indicates that volatilization from moist soil surfaces is not expected(SRC). Ethylene bis(tetrabromophthalimide) is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.5X10-22 mm Hg(SRC), determined from a fragment constant method(3).

Occupational exposure to ethylene bis(tetrabromophthalimide) may occur through inhalation and dermal contact with this compound at workplaces where ethylene bis(tetrabromophthalimide) is produced or used(SRC). Occupational exposure would be expected to be minimal(SRC), since ethylene bis(tetrabromophthalimide) is manufactured in a closed system(1).

14C-labelled BT93 was administered orally by gavage in corn oil to 5 female Sprague-Dawley rats for 14 consecutive days. Two rats were sacrificed 24 hr after the last dose; remainder sacrificed 7, 14, and 30 days after the last dose. Liver, kidney, brain, leg muscle and body fat were collected at each sacrifice. Urine, feces and expired air was collected 24 hr after the last dose. The compound was excreted mainly in the feces (approximately 65% of the total dose). Approximately 15% of the total dose was found in the urine. The amount of the radiolabel excreted in expired air was negligible. A minor trace amount of 14C-label was temporarily detected in tissues; residues were <0.5 ppm in any tissue. Tissues from animals sacrificed during the withdrawal period showed a dissipation of residue levels in all tissues within the 30 withdrawal period. Kidney level went from 0.32 ppm 24 hr after the last dose to 0.043 ppm at day 30 post dosing; liver went from 0.424 ppm 24 hr after the last dose to 0.024 ppm at day 30 post dosing.

SYMPTOMS: This compound may cause transient eye irritation. ACUTE/CHRONIC HAZARDS: When heated to decomposition it emits toxic fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

Adhesive manufacturing|1H-Isoindole-1,3(2H)-dione, 2,2'-(1,2-ethanediyl)bis[4,5,6,7-tetrabromo-: ACTIVE|/Ethylene bis tetrabromophthalimide/ (EBTBP) is manufactured in a closed system.