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Acesulfame potassium

Acesulfame potassium structure

CAS No:
55589-62-3
Formula:
C4H5NO4S.K
Chemical Name:
Acesulfame potassium
Synonyms:
1,2,3-Oxathiazin-4(3H)-one,6-methyl-,2,2-dioxide,potassium salt (1:1);1,2,3-Oxathiazin-4(3H)-one,6-methyl-,2,2-dioxide,potassium salt;Acesulfame K;Sunett;Acesulfame potassium;6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide potassium salt;Potassium acesulfame;Sunnett;Otizon;E 950;Sweet One;Potassium acesulfamate;Sunett D;Potassium 3,4-dihydro-6-methyl-1,2,3-oxathiazine-4-one-2,2-dioxide;Sunnet Pharma Grade D;124030-40-6;133249-02-2;1017787-12-0
Categories:
Cosmetic Ingredient > Fragrance Ingredient

Description

Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice[1].

Acesulfame potassium Basic Attributes

Molecular Weight：

201.24200

Exact Mass：

200.95000

EC Number：

259-715-3

HScode：

2934999090

Characteristics

PSA：

68.82000

XLogP3：

0.47680

Appearance：

White, odorless, free flowing crystalline powder

Density：

1.512g/cm3

Melting Point：

68 °C

Boiling Point：

332.7ºC at 760 mmHg

Flash Point：

155ºC

Water Solubility：

Very soluble in water, very slightly soluble in ethanol

Storage Conditions：

0-6ºC

Toxicity：

LD50 in rats (mg/kg): 7431 orally, 2243 i.p. (Mayer, Kemper)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R36/37/38

safety instructions：

S26

RTECS Number：

RP4489165

Precautionary statement(s)：

P264, P280, P305+P351+P338, P33, P313

Hazard Statements：

H319

Acesulfame potassium Use and Manufacturing

Methods of Manufacturing

A 50percent SO3-dichloromethane solution and a 21.7percent intermediate-dichloromethane solution were used.The high-pressure liquid advection pump continuously feeds into the microchannel reactor 1 for the cyclization reaction.The key reaction component of SO3 and the intermediate reaction molar ratio of 6:1, cyclizing agent and the intermediate solution of the feed volume ratio of 1:1.6;The cyclization solution enters the microchannel reactor 2 for hydrolysis, and the amount of water is 5 times the excess SO3.The control temperatures of the cyclization and hydrolysis reactors were 4.5°C and 1.5°C, respectively.The liquefaction hourly space velocity of the cyclization reactor was 1890 h-1.The product flowing from the hydrolysis reactor is phase separated, Dichloromethane extraction, water extraction three times and then neutralized by KOH aqueous solution, taking a little neutralizing solution diluted with water to a certain volume, The ASK concentration was analyzed by liquid chromatography and the ASK yield was calculated.The yield was 56.7percent.

Uses

'New generation', heat-stable sweetener that has not been suspected to cause cancer nor be genotoxic. Allelic variation of the Tas1r3 gene affects behavioral taste responses to this molecule, suggesting that it is a T1R3 receptor ligand.

Material

Triethylamine

Acetylacetone

Sulfamic acid

Potassium carbonate

Price Analysis

Make your Acesulfame potassium purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Acesulfame potassium prices .

Drug Function and Efficacy

non-nutritive sweetener

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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Registered Holders

Vitasweet Co., Ltd.

China
Active
Anhui Jinhe Industrial Co., Ltd.

China
Inactive

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