Sulfamic acid

97.0937

97.09

226-218-8

9NFU33906Q

0328

1871

2967

DTXSID6034005

ORTHORHOMBIC CRYSTALS|WHITE CRYSTALLINE SOLID|Granular grade is off-white in color

28111990.9

88.77

0.529

white crystalline powder

2.15 g/cm³

205 °C

247°C

205°C

1.553

H2O: 146.8 g/L (20 ºC)

Store in a cool, dry place. Store in a tightly closed container. Do not store in metal containers.

oral - rat LD50: 3160 mg / kg; oral - mouse LD50: 1312 mg / kg

Flammability Limits = 9.3 vol%

ODORLESS

1N, pH=0.41; 0.75N, pH=0.5; 0.5N, pH=0.63; 0.25N, pH=0.87; 0.1N, pH=1.18; 0.05N, pH=1.41; 0.01N, pH=2.02

Dissociation constant at 25 °C = 0.101

NON-VOLATILE; NONHYDROSCOPIC; AQ SOLN ARE HIGHLY IONIZED GIVING PH VALUES LOWER THAN SOLN OF FORMIC, PHOSPHORIC, & OXALIC ACIDS|SLOWLY HYDROLYZES IN SOLN TO FORM AMMONIUM BISULFATE|Decomposition temperature = 209 °C|Heat of formation = -6.749X10+8 J/kmol|For more Other Experimental Properties (Complete) data for SULFAMIC ACID (6 total), please visit the HSDB record page.

Moderately soluble in water [Hawley].

Acids, Strong Non-oxidizing

Known Catalytic Activity

SULFAMIC ACID reacts exothermically with bases. Aqueous solutions are acidic and corrosive.

1.53x10+7 J/kmol

Flammability Limits = 9.3 vol%

H2SO4 (3wt%) and HCl (3wt%) are 2.6 and 4.2 times more corrosive, respectively, than a 3 wt% solution of sulfamic acid on 1010 steel. On the same scale, H2SO4 and HCl (3wt% solutions) are 1.5 and 6.7, respectively, times more corrosive on copper; 1.5 and 2.8 more corrosive on brass; 4.0 and 7.0 more corrosive on bronze; 0.6 and 5.3 more corrosive on aluminum.

III

8

UN 2967 8/PG 3

1

R36/38; R52/53

S26-S28-S61-S28A

WO5950000

Xi

Store only in original container. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Dry. Store in an area without drain or sewer access.

Stable.

P273-P305 + P351 + P338

H315-H319-H412

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|Package Lots: Place in a separate labeled container for recycling or disposal by burning in a furnace equipped with an afterburner and scrubber. Small Quantities: Wear eye protection, laboratory coat and nitrile rubber gloves. Work in the fume hood. Sift slowly into a large container of cold water, with agitation. When dissolved, neutralize with sodium carbonate and pour into drain with at least 50 times its volume of water.

Chlorination of amidosulfuric acid or acidic ammonium chloride solutions gives the powerfully explosive oil nitrogen trichloride.|Heating mixtures of barium, potassium or sodium amidosulfates or amidosulfuric acid, with sodium or potassium nitrates or nitrites, leads to reactions which may be explosive.|Mixing with fuming nitric acid results in violent release of nitrous oxide.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)|Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire. Risk of explosion on contact with incompatible substances. See Chemical Dangers.

|Warning|H315: Causes skin irritation [Warning Skin corrosion/irritation]|P264, P273, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362, and P501|Danger|H315 (99.9%): Causes skin irritation [Warning Skin corrosion/irritation]|P260, P264, P270, P273, P280, P302+P352, P305+P351+P338, P314, P321, P332+P313, P337+P313, P362, and P501|Aggregated GHS information provided by 3943 companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. (ERG, 2016)

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use dry chemical, dry sand, or carbon dioxide. Do not use water on material itself. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog.

Wear eye protection, laboratory coat and nitrile rubber gloves. Clean up with dust pan and brush. May be flushed away to waste with at least 50 vol of water or mixed with sand and disposed or as normal refuse.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers.|Personnel protection: Avoid breathing dusts, and fumes from burning material. Avoid bodily contact with the material. ... If contact with the material anticipated, wear appropriate chemical protective clothing.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for SULFAMIC ACID (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Dust or solution irritates the eyes, skin and mucous membranes. Prolonged exposure of skin to the acid may cause irritation.

Personal protection: face shield. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Cautiously neutralize remainder. Then store and dispose of according to local regulations.

Store only in original container. Separated from food and feedstuffs and incompatible materials. See Chemical Dangers. Dry. Store in an area without drain or sewer access.

A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

The substance is severely irritating to the eyes. The substance is irritating to the skin. The substance may be irritating to the respiratory tract.

NO open flames. NO contact with incompatible materials: See Chemical Dangers

Use local exhaust or breathing protection.

Protective gloves. Protective clothing.

Wear safety goggles or face shield.

SUBSTANCE WHICH MIGRATES TO FOOD FROM PACKAGING MATERIALS.

3= MODERATELY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG, BETWEEN 1 OZ & 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB).

Pesticides used to destroy unwanted vegetation, especially various types of weeds, grasses (POACEAE), and woody plants. Some plants develop HERBICIDE RESISTANCE. (See all compounds classified as Herbicides.)|Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)

Typical analysis, in 1981, of the E.I. du Pont de Nemours & Co. Inc products - Crystal grade: 0.2 wt% sulfates, 0.001 wt% iron, and 0.001 wt% insoluble matter; Granular grade: 3.5 wt% ammonium bisulfate, 3.5 wt% sulfuric acid, 0.1 wt% urea, 0.15 wt% magnesium, and 0.2 wt% sulfur trioxide

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)|Corrosives

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim calm and warm. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. (ERG, 2016)

Fresh air, rest. Seek medical attention if you feel unwell.

Rinse skin with plenty of water or shower. Refer for medical attention if skin irritation occurs.

Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.

SYMPTOMATOLOGY (...INGESTION OR SKIN CONTACT): 1. CORROSION OF MUCOUS MEMBRANES OF MOUTH, THROAT...ESOPHAGUS, WITH...PAIN & DYSPHAGIA. NECROTIC AREAS...GRAYISH WHITE BUT SOON...BLACKISH DISCOLORATION...& SOMETIMES SHRUNKEN OR WRINKLED TEXTURE. /ACID/|SYMPTOMATOLOGY.../INGESTION/: 2. EPIGASTRIC PAIN...MAY BE ASSOC WITH NAUSEA & VOMITING...INTENSE THIRST. 3. CIRCULATORY COLLAPSE...CLAMMY SKIN, WEAK & RAPID PULSE, SHALLOW RESP...SCANTY URINE. ...SHOCK IS OFTEN...CAUSE OF DEATH. 4. ASPHYXIAL DEATH DUE TO GLOTTIC EDEMA. /ACID/|SYMPTOMATOLOGY.../INGESTION/: 5. ULCERATION OF ALL MEMBRANES & TISSUES WITH WHICH ACID COMES IN CONTACT. ULCERATED AREAS OFTEN PERFORATE, LEADING TO MEDIASTINITIS & PERITONITIS. 6. LATE ESOPHAGEAL, GASTRIC & PYLORIC STRICTURES & STENOSIS...MAY REQUIRE...SURGICAL REPAIR, SHOULD BE ANTICIPATED. /ACID/|SYMPTOMATOLOGY.../INGESTION/: 6. ...PERMANENT SCARS MAY...APPEAR CORNEA, SKIN & OROPHARYNX. 7. UNCORRECTED CIRCULATORY COLLAPSE OF SEVERAL HR...MAY LEAD TO RENAL FAILURE & ISCHEMIC LESIONS IN LIVER & HEART. /ACID/|For more Human Toxicity Excerpts (Complete) data for SULFAMIC ACID (6 total), please visit the HSDB record page.

amidosulfonic acid

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Cough. Sore throat.

Redness. Pain.

Redness. Pain. Burns.

99.5% Crystal or granular technical grades|Typical analysis in 1981 of the E.I. du Pont de Nemours & Co. Inc products: 99.7% Crystal grade, 92.2% Granular grade

Acid Cleaning|Sulfamic acid: ACTIVE|...ACID OR ITS AMMONIUM SALT...RECOMMENDED FOR FLAMEPROOFING FABRICS & WOOD. METAL SALTS...USED IN ELECTROPLATING. AMMONIUM SULFAMATE IS ALSO WIDELY USED AS WEED KILLER...

SEPARATION AND IDENTIFICATION OF 12 ANTIMICROBIAL COMPOUNDS BY TLC.

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives|Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern|Health Hazards -> Corrosives