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Home > Encyclopedia > Azetidine hydrochloride

Azetidine hydrochloride

Azetidine hydrochloride structure

Azetidine hydrochloride 

structure
  • CAS No:

    36520-39-5

  • Formula:

    C3H8ClN

  • Chemical Name:

    Azetidine hydrochloride

  • Synonyms:

    AZETIDINE HCL;AZETIDINE HYDROCHLORIDE;TRIMETHYLENEIMINE HYDROCHLORIDE;Azetidine (trimethyleneimine) hydrochloride;Azetidine hydrochloride ,99%;Azetidine hydrochloride ,98%;Trimethylene imine hydrochloride, 1,3-Propylenimine hydrochloride, Azacyclobutane hydrochloride;azetadine hydrochloride

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

A four-membered ring nitrogen-containing heterocycle. Useful building block in the synthesis of polypeptides and other nitrogen containing compounds with potential biological properties.


White powder


Azetidine derivatives are an essential class of aza-heterocyclic compounds with various biological activities and have been widely used as building blocks in pharmacological research. Although azetidine has the simplest structure, it is only commercially available in small quantities and at a high price. In addition, this compound is hard to synthesize for several reasons, such as cyclization of the four-membered ring, stability of the ring, and low boiling point[1].

Azetidine hydrochloride Basic Attributes

93.55

93.0345

627-415-5

White to Almost white

29339900

Characteristics

12.03

1.1105

White powder

>300 °C(lit.)

103.8ºC at 760 mmHg

16.6ºC

Soluble in water (103.8°C at 760 mmHg).

Inert atmosphere,2-8°C

Safety Information

IRRITANT, HYGROSCOPIC

3

Xi

26

Xi

S26

36/37/38

UN1325

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 44 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Azetidine hydrochloride Use and Manufacturing

Basic building block for synthesizing azetidines.1,2


Azetidine hydrochloride is a four-membered ring nitrogen-containing heterocycle. Useful building block in the synthesis of polypeptides and other nitrogen containing compounds with potential biological properties.


Azetidine hydrochloride is a building block for azetidine synthesis and a pharmaceutical intermediate.

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