5-(3-Methylphenoxy)-2(1H)-pyrimidinone
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5-(3-Methylphenoxy)-2(1H)-pyrimidinone
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CAS No:
41964-07-2
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Formula:
C11H10N2O2
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Chemical Name:
5-(3-Methylphenoxy)-2(1H)-pyrimidinone
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Synonyms:
2(1H)-Pyrimidinone,5-(3-methylphenoxy)-;5-(3-Methylphenoxy)-2(1H)-pyrimidinone;Tolimidone;CP 26154;NSC 314335;MLR 1023
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CAS No:
5-(3-Methylphenoxy)-2(1H)-pyrimidinone Basic Attributes
202.21
202.21
200-258-5
MU3JD8E9IS
314335
DTXSID50194786
5-(3-Methylphenoxy)-2(1H)-pyrimidinone Use and Manufacturing
Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.
Computed Properties
Molecular Weight:202.21
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:202.074227566
Monoisotopic Mass:202.074227566
Topological Polar Surface Area:50.7
Heavy Atom Count:15
Complexity:310
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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