Nifekalant hydrochloride
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Nifekalant hydrochloride
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CAS No:
130656-51-8
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Formula:
C19H27N5O5.ClH
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Chemical Name:
Nifekalant hydrochloride
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Synonyms:
2,4(1H,3H)-Pyrimidinedione,6-[[2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl]amino]-1,3-dimethyl-,hydrochloride (1:1);2,4(1H,3H)-Pyrimidinedione,6-[[2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl]amino]-1,3-dimethyl-,monohydrochloride;MS 551;Shinbit;Nifekalant hydrochloride
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CAS No:
Nifekalant hydrochloride Basic Attributes
441.91
441.1778967 g/mol
1533716-785-6
TPP5R0MDQS
DTXSID9046495|DTXSID7048374
Drug Information
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)
1,3-dimethyl-6-((2-(N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino)ethylamino)-2,4(1H),3H)-pyrimidinedione hydrochloride
Nifekalant hydrochloride Use and Manufacturing
Nifekalant Hydrochloride is a class III antiarrhythmic agent. Nifekalant Hydrochloride is used in the treatment of patients with extensive anterior infarction and severe ventricular dysfunction.
Computed Properties
Molecular Weight:441.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:10
Exact Mass:441.1778967
Monoisotopic Mass:441.1778967
Topological Polar Surface Area:122
Heavy Atom Count:30
Complexity:613
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Unspecified
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