Palovarotene
-
Palovarotene
structure -
-
CAS No:
410528-02-8
-
Formula:
C27H30N2O2
-
Chemical Name:
Palovarotene
-
Synonyms:
Benzoic acid,4-[(1E)-2-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-2-naphthalenyl]ethenyl]-;4-[(1E)-2-[5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-2-naphthalenyl]ethenyl]benzoic acid;R 667;Ro 3300074;Palovarotene;4-{(1E)-2-[5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-5,6,7,8-tetrahydronaphthalen-2-yl]ethenyl}benzoicacid;CLM 001;IPN 60120;Sohonos
- Categories:
-
CAS No:
Description
Palovarotene has been used in trials studying the treatment of Fibrodysplasia Ossificans Progressiva.|Palovarotene is an orally available, selective retinoic acid receptor gamma agonist. Palovarotene selectively binds to the gamma retinoid agonist, thereby reducing inflammation and enhancing repair.
Drug Information
Treatment of multiple osteochondromas|Treatment of fibrodysplasia ossificans progressiva
Palovarotene
Palovarotene Use and Manufacturing
Human drugs -> Rare disease (orphan)|Human Drugs -> EU pediatric investigation plans
Computed Properties
Molecular Weight:414.5
XLogP3:6.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:414.230728204
Monoisotopic Mass:414.230728204
Topological Polar Surface Area:55.1
Heavy Atom Count:31
Complexity:662
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of Palovarotene
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 410528-02-8Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
Methyl 1-(2,3-dihydroxypropyl)-1,4-dihydro-4-oxo-3-(phenylmethoxy)-2-pyridinecarboxylate
1206102-07-9
-
(4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione
1206102-10-4
-
N-(2,3-dimethylphenyl)-2-methoxybenzamide
331270-89-4
-
(5Z)-1-(4-bromophenyl)-5-(furan-2-ylmethylidene)-3-phenyl-2-sulfanylidene-1,3-diazinane-4,6-dione Formula
414908-02-4
-
ethyl 2-[3-(trifluoromethyl)pyrazol-1-yl]acetate Formula
380872-50-4
-
N-(1-hydroxy-2-methylpropan-2-yl)-4-methoxybenzamide Formula
94615-60-8
-
2-(1H-indol-3-yl)-N-(5-methyl-1,3-thiazol-2-yl)acetamide Structure
784170-07-6
-
1-(4-tert-butylphenyl)sulfonyl-4-(2,5-dimethylphenyl)piperazine Structure
693229-10-6
-
What is 3-[(4-butylphenyl)sulfamoyl]benzoic acid
377769-55-6
-
What is 3H-thieno[2,3-d]pyrimidine-4-thione
14080-55-8