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(Hydroxymethyl)phosphonate

(Hydroxymethyl)phosphonate structure

(Hydroxymethyl)phosphonate 

structure
  • CAS No:

    2617-47-2

  • Formula:

    CH5O4P

  • Chemical Name:

    (Hydroxymethyl)phosphonate

  • Synonyms:

    Phosphonic acid,P-(hydroxymethyl)-;Phosphonic acid,(hydroxymethyl)-;P-(Hydroxymethyl)phosphonic acid;(Hydroxymethyl)phosphonate;Methanehydroxyphosphonic acid;(Hydroxymethyl)phosphonic acid;Hydroxymethanephosphonic acid;NSC 41905;NSC 63035;Phosphonomethanol

  • Categories:

    Organic Chemistry  >  Phosphines

Description

Hydroxymethylphosphonic acid is a phosphonic acid having a hydroxymethyl group attached to the phosphorus. It has a role as an EC 3.11.1.3 (phosphonopyruvate hydrolase) inhibitor. It is a member of phosphonic acids and a one-carbon compound. It derives from a phosphonic acid. It is a conjugate acid of a hydroxymethylphosphonate(1-).

(Hydroxymethyl)phosphonate Basic Attributes

112.02

112.02

220-047-2

DO34G523HF

63035|41905

DTXSID5062554

Characteristics

77.8 Ų

1.655 g/cm3 @ Temp: 25.5 °C

84.5-86 °C

79-81 °C @ Press: 10 Torr

1.4970

2.58±0.10

Safety Information

|Danger|H290 (75%): May be corrosive to metals [Warning Corrosive to Metals]|P201, P202, P234, P260, P261, P264, P272, P280, P281, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P321, P333+P313, P363, P390, P404, P405, and P501|Aggregated GHS information provided by 4 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

hydroxymethylphosphonate

(Hydroxymethyl)phosphonate Use and Manufacturing

Uses

Phosphonomethanol has been used in the investigation on the stereochemistry of 2-Hydroxyethylphosphonate Dioxygenase.

Phosphonic acid, P-(hydroxymethyl)-: ACTIVE

Computed Properties

Molecular Weight:112.02
XLogP3:-2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:111.99254563
Monoisotopic Mass:111.99254563
Topological Polar Surface Area:77.8
Heavy Atom Count:6
Complexity:71.6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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