Monobromobimane
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Monobromobimane
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CAS No:
71418-44-5
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Formula:
C10H11BrN2O2
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Chemical Name:
Monobromobimane
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Synonyms:
1H,7H-Pyrazolo[1,2-a]pyrazole-1,7-dione,3-(bromomethyl)-2,5,6-trimethyl-;3-(Bromomethyl)-2,5,6-trimethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione;Monobromobimane;Thiolyte MB;Bromobimane;NSC 608544
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CAS No:
Description
Monobromobimane is a pyrazolopyrazole that consists of 1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione bearing three methyl substituents at positions 2, 5 and 6 as well as a bromomethyl substituent at the 3-position. It has a role as a fluorochrome. It is an organobromine compound and a pyrazolopyrazole.
Characteristics
42.96000
1.01710
1.66±0.1 g/cm3
142 °C @ Solvent: Ethyl acetate
327.8±44.0 °C(Predicted)
152.1ºC
1.64
-3.36±0.70
Drug Information
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags. (See all compounds classified as Fluorescent Dyes.)
bromobimane
Monobromobimane Use and Manufacturing
Monobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The absorption and emission maxima for monobromobimane are 398 and 490 nm, respectively.
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