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Pyriprole

Pyriprole structure

CAS No:
394730-71-3
Formula:
C18H10Cl2F5N5S
Chemical Name:
Pyriprole
Synonyms:
1H-Pyrazole-3-carbonitrile,1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(difluoromethyl)thio]-5-[(2-pyridinylmethyl)amino]-;1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-4-[(difluoromethyl)thio]-5-[(2-pyridinylmethyl)amino]-1H-pyrazole-3-carbonitrile;Pyriprole;Prac-tic
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Pyriprole is a member of pyrazoles and a ring assembly.

Pyriprole Basic Attributes

Molecular Weight：

494.26900

Exact Mass：

494.27

UNII：

69OX73ZVJN

DSSTox ID：

DTXSID20192613

ATC Code：

QP53AX26

Characteristics

PSA：

91.83000

XLogP3：

6.46438

Density：

1.588g/cm3

Boiling Point：

517.748ºC

Flash Point：

266.925ºC

Refractive Index：

1.623

Drug Information

Drug Indication：

Treatment and prevention of flea infestation (Ctenocephalides canis and C. felis) in dogs. Efficacy against new infestations with fleas persists for a minimum of 4 weeks.Treatment and prevention of tick infestation (Ixodes ricinus, Rhipicephalus sanguineus, Ixodes scapularis, Dermacentor reticulatus, Dermacentor variabilis, Amblyomma americanum) in dogs. Efficacy against ticks persists for 4 weeks.

MeSH Entry Terms：

pyriprole

Pyriprole Use and Manufacturing

Use Classification：

Veterinary drugs -> Prac-tic -> EMA Drug Category|Ectoparasiticides for topical use, incl. insecticides -> Veterinary pharmacotherapeutic group

Computed Properties

Molecular Weight:494.3
XLogP3:6.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:492.9954127
Monoisotopic Mass:492.9954127
Topological Polar Surface Area:91.8
Heavy Atom Count:31
Complexity:639
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes