N-(2-Methylpropyl)-1-butanamine

Pesticide and dye manufacturing: widely used in insecticide production, suitable for pest control of crops such as rice, fruits and vegetables.

Organic synthesis intermediates: used as reaction intermediates in the synthesis of drug molecules or fine chemicals

1. Alkylation method

Reaction principle

Using n-butylamine and isobutyl halides as raw materials, alkylation reaction is carried out under alkaline conditions to produce the target product 1.

Example process

Preparation of N-Isobutylbutamine via Alkylation Step by Reaction of Isobutyl Pyrophosphate (IBJP) with Butanol

2. Catalytic amination method

Raw materials and conditions

Referring to the synthesis process of isobutylamine (such as catalytic dehydration of isobutanol and ammonia or catalytic hydrogenation of isobutyraldehyde and ammonia), the raw materials are adjusted to butanol and isobutylamine, and amination reaction is carried out through a fixed bed reactor under the action of nickel based or cobalt based catalysts supported on γ - Al ₂ O3.

Optimization direction

The generation ratio of primary, secondary, and tertiary amines can be controlled by adjusting the reaction temperature (such as 280-320 ℃), pressure (such as 4 MPa), and raw material ratio

3. Green process technology

Recycling of by-products

The water generated in some processes can be reused through a recycling system to reduce the cost of waste liquid treatment.

Catalyst recycling

Adopting recyclable catalysts (such as supported catalysts in patented technology) to reduce resource consumption and improve industrial efficiency

Molecular Weight:129.24
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:129.151749610
Monoisotopic Mass:129.151749610
Topological Polar Surface Area:12
Heavy Atom Count:9
Complexity:50.5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes