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Tris(isopropylphenyl) phosphate

Tris(isopropylphenyl) phosphate structure

Tris(isopropylphenyl) phosphate 

structure
  • CAS No:

    26967-76-0

  • Formula:

    C27H33O4P

  • Chemical Name:

    Tris(isopropylphenyl) phosphate

  • Synonyms:

    Phenol,(1-methylethyl)-,phosphate (3:1);Tris(isopropylphenyl) phosphate;Tri(isopropylphenyl) phosphate;Reofos 95;Triisopropyl benzene phosphate

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Tris(4-isopropylphenyl)phosphate is a yellow waxy solid.|Liquid


Tris(4-isopropylphenyl)phosphate is a yellow waxy solid.

Tris(isopropylphenyl) phosphate Basic Attributes

452.52200

452.21164653 g/mol

273-066-3|248-147-1|219-703-0

Y3H2FDX0NW

3077

DTXSID4028880|DTXSID80858783|DTXSID50858795

Characteristics

54.57000

8.70170

1.159 g/cm3 @ Temp: 20 °C

-25 °C

220-270 °C @ Press: 4.0 Torr

174.344ºC

0mmHg at 25°C

No rapid reaction with air. No rapid reaction with water.

Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

Organophosphates, such as TRIS(4-ISOPROPYLPHENYL)PHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Safety Information

III

9

UN 3077

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)

|Warning|H317 (75.79%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P201, P202, P260, P261, P272, P273, P280, P281, P302+P352, P308+P313, P314, P321, P333+P313, P363, P391, P405, and P501|Aggregated GHS information provided by 1242 companies from 36 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H361f: Suspected of damaging fertility [Warning Reproductive toxicity]|P201, P202, P260, P281, P308+P313, P314, P405, and P501|H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]|P260, P314, and P501

To extinguish a fire involving this chemical you may use a dry chemical, carbon dioxide, foam or halon extinguisher; a water spray may also be used. (NTP, 1992)

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves. RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. RECOMMENDED GLOVE MATERIALS: Permeation data indicate that butyl rubber gloves may provide protection to contact with this compound. Butyl rubber over latex gloves is recommended. However, if this chemical makes direct contact with your gloves, or if a tear, hole or puncture develops, remove them at once. (NTP, 1992)

Drug Information

Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, administer a slurry of activated charcoal in water and simultaneously call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Tris(isopropylphenyl) phosphate Use and Manufacturing

Uses

Adhesives and sealant chemicals


Automotive care products

Production

1,000,000 - 10,000,000 lb

Adhesive manufacturing|Phenol, isopropylated, phosphate (3:1): ACTIVE|TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.

Computed Properties

Molecular Weight:452.5
XLogP3:7.4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:452.21164653
Monoisotopic Mass:452.21164653
Topological Polar Surface Area:44.8
Heavy Atom Count:32
Complexity:500
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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