Chromic acid (H2Cr2O7), zinc salt (1:1)

281.36800

279.774554 g/mol

237-843-0

A14W55Z1DY

DTXSID5065695

123.63000

-0.78370

3.4 at 20 °C

Soluble in acids and liquid ammonia

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/

Reddish-brown crystal; hygroscopic; mol wt: 335.41; decomposes in hot water; very soluble in cold water; insoluble in alcohol, ether; soluble in acids. /Zinc dichromate trihydrate/|Orange-yellow powder; soluble in acids and hot water, insoluble in alcohol and ether /Zinc dichromate trihydrate/|Harsh metallic taste /Zinc dichromate trihydrate/|When heated to decomposition it emits toxic vapors of zinc and chromium

II

6.1(a)

UN 3288

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D007, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste. /Chromium/|SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.|The following wastewater treatment technology has been investigated for chromium: Concentration process: Biological Treatment. /Chromium/|The following wastewater treatment technology has been investigated for chromium: Concentration process: Chemical Precipitation. /Chromium/|For more Disposal Methods (Complete) data for ZINC DICHROMATE (14 total), please visit the HSDB record page.

Combustible, organic, or other readily oxidizable materials (paper, wood, sulfur, aluminum, plastics, etc.); corrosive to metals. /Chromic acid and chromates/|Hydrazine is decomposed explosively by chromates and chromic anhydride. /Chromates/

DHHS/ATSDR; Toxicological profile for chromium (September 2012).[DHHS/ATSDR; Toxicological profile for chromium (September 2012); Available from, as of February 8, 2016: ww.atsdr.cdc.gov/toxprofiles/tp7.pdf]|USEPA; Ambient Water Quality Criteria Doc: Zinc (1980) EPA 400/5-80-079|USEPA; Ambient Water Quality Criteria Doc: Zinc (1987) EPA 440/5-87-003

Workers ... should wear personal protective equipment (acid-proof protective clothing, footwear, gloves and goggles). /Oxidizing substances/|Handle in effective fume removal device from behind explosion-resistant barrier. Use face shield. /Oxidizers/|Impervious gloves, aprons, and footwear shall be worn at operations where solutions of chromium (VI) may contact the skin. Protective gloves shall be worn at operations where dry compounds of chromium (VI) are handled and may contact the skin. /Cr(VI)/|Protective clothing: Coveralls or other full-body protective clothing shall be worn in areas where there is occupational exposure to chromium (VI). Protective clothing shall be changed at least daily at the end of the shift and more frequently if it should become grossly contaminated. /Cr(VI)/|For more Personal Protective Equipment (PPE) (Complete) data for ZINC DICHROMATE (11 total), please visit the HSDB record page.

/When fire fighting wear/ self-contained breathing apparatus, with a full facepiece, operated in pressure-demand or other positive pressure mode. /Chromic acid & chromates/

Cr(VI) cmpd in waste sludge are completely removed by redn by carbon at 600 °C. /Chromium VI/|Persons not wearing protective equipment and clothing should be restricted from areas of spills until cleanup has been completed. If chromic acid or chromates are spilled, the following steps should be taken: 1. Ventilate area of spill. 2. Collect spilled material in the most convenient and safe manner and deposit in sealed containers for reclamation or for disposal in a secured sanitary landfill. Liquid containing chromic acid or chromates should be absorbed in vermiculite, dry sand, earth, or a similar material. /Chromic acid and chromates/|PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal ... The plastic bag should be sealed immediately ... The sealed bag should be labelled properly ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. /Chemical Carcinogens/

SRP: Contaminated protective clothing should be segregated in a manner such that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.|Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises. /Chromic acid and cromates/|Work clothing that becomes wet or significantly contaminated should be removed and replaced. /Chromic acid and cromates; Chromium(II) compounds (as Cr); Chromium(III) compounds/|The worker should immediately wash the skin when it becomes contaminated. /Chromic acid and chromates; Chromium(II) compounds (as Cr); Chromium(III) compounds/|For more Preventive Measures (Complete) data for ZINC DICHROMATE (13 total), please visit the HSDB record page.

PRECAUTIONS FOR "CARCINOGENS": Procurement ... of unduly large amt ... should be avoided. To avoid spilling, carcinogens should be transported in securely sealed glass bottles or ampoules, which should themselves be placed inside strong screw-cap or snap-top container that will not open when dropped & will resist attack from the carcinogen. Both bottle & the outside container should be appropriately labelled. ... National post offices, railway companies, road haulage companies & airlines have regulations governing transport of hazardous materials. These authorities should be consulted before ... material is shipped. /Chemical Carcinogens/|PRECAUTIONS FOR "CARCINOGENS": When no regulations exist, the following procedure must be adopted. The carcinogen should be enclosed in a securely sealed, watertight container (primary container), which should be enclosed in a second, unbreakable, leakproof container that will withstand chem attack from the carcinogen (secondary container). The space between primary & secondary container should be filled with absorbent material, which would withstand chem attack from the carcinogen & is sufficient to absorb the entire contents of the primary container in the event of breakage or leakage. Each secondary container should then be enclosed in a strong outer box. The space between the secondary container & the outer box should be filled with an appropriate quantity of shock-absorbent material. Sender should use fastest & most secure form of transport & notify recipient of its departure. If parcel is not received when expected, carrier should be informed so that immediate effort can be made to find it. Traffic schedules should be consulted to avoid ... arrival on weekend or holiday ... /Chemical Carcinogens/

Chromic acid mist & chromate dusts may cause severe irritation of the nose, throat, bronchial tubes, and lung. /Chromic acid mist & chromate dusts/

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 1 mg/cu m. /Chromium metal and insoluble salts, as Cr/|Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 0.5 mg/cu m. /Chromium(II) compounds, as Cr/|Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 0.5 mg/cu m. /Chromium(III) compounds, as Cr/|Permissible Exposure Limit: Table Z-2 Acceptable Ceiling Concentration: 1 mg/10 cu m. /Chromic acid and chromates (as CrO3)/

Recommended Exposure Limit: 8-hour Time-Weighted Average: 0.5 mg Cr/cu m. /Chromium metal, chromium(II) and chromium(III) compounds/|Recommended Exposure Limit: 8-hour Time-Weighted Average: 0.0002 mg Cr(VI)/cu m. NIOSH considers all Cr(VI) compounds (including chromic acid, tert-butyl chromate, zinc chromate, and chromyl chloride) to be potential occupational carcinogens. /All hexavalent chromium (Cr(VI) compounds/|NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concentration. /Chromic acid and chromates/

... Substances for which a Federal Register notice has been published that included consideration of the serious health effects, including cancer, from ambient air exposure to the substance. Chromium is included on this list. /Chromium/|Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Chromium compounds is included on this list. /Chromium compounds/

D007; A waste containing chromium may or may not be characterized as a hazardous waste following testing by the Toxicity Characteristic Leaching Procedure as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations. /Chromium/

D007; A solid waste containing chromium may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Chromium/

IDENTIFICATION AND USE: Zinc dichromate is a orange-yellow powder. Zinc chromates are employed primarily in priming paints used for metals, for which they provide resistance against corrosion. HUMAN EXPOSURE AND TOXICITY: Zinc chromate appeared to be the most potent carcinogen, based on studies of lung cancer mortality in chromate pigment workers. In 28 spray painters the urine studies showed elevated chromium concentrations as a result of using zinc chromate containing wash primers without taking measures to protect themselves from contamination. Health complaints like increased tiredness, deterioration in short term memory, and headache were equally frequent in spray painters and comparisons. Epidemiologic studies have shown an increased incidence of lung cancer among chromate pigment workers, however, the number of cancer cases was small and the concentrations of zinc-chromate were not known. ANIMAL STUDIES: Lung tumors have been induced by zinc chromates in laboratory animals and zinc-chromate has shown mutagenic activity in bacterial test systems. Deaths in cattle believed to have had access to zinc chromate paste have been recorded in New Zealand. A daily dose of 30-40 mg/kg body weight produced severe chronic poisoning in young calves within one month. The acute lethal dose for adult cattle is about 20 times this amount. The outstanding clinical feature of the condition produced was profuse scouring, leading in chronic cases to severe dehydration and a low terminal blood pressure. Changes in the alimentary tract were the most marked post mortem finding. In acute poisoning, there was severe congestion and inflammation throughout the intestines and sloughing of the gastric mucous membranes. In chronic poisoning, congestion and inflammation were present only in the stomach; the rumen and abomasum in particular showing severe ulceration and near perforation.

NIOSH (NOES Survey 1981-1983) has statistically estimated that 349 workers (16 of these are female) were potentially exposed to zinc dichromate in the US(1).

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W TKO. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) or lorazepam (Ativan) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/|/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Inorganic acids and related compounds/|For more Antidote and Emergency Treatment (Complete) data for ZINC DICHROMATE (6 total), please visit the HSDB record page.

/EPIDEMIOLOGY STUDIES/ A study was conducted to assess exposure to solvent mixtures and subjective symptoms reported by painters engaged in spray painting activities. The study subjects included 163 male workers, 105 of whom were exposed as spray painters with at least 10 years of working experience, and 458 workers without any relevant occupational contact with solvents. The responses to questions did not produce a typical picture of neuropsychiatric symptoms in the exposed painters. The differential analysis of the incidence of symptoms showed that age was more important than length of solvent exposure. Only in the case of methyl-hippuric-acid in urine spot samples did the spray painters show a higher mean value than comparisons, indicating recent xylene exposure. In 28 spray painters the urine studies showed elevated chromium concentrations as a result of using zinc chromate containing wash primers without taking measures to protect themselves from contamination. Health complaints like increased tiredness, deterioration in short term memory, and headache were equally frequent in spray painters and comparisons.|/OTHER TOXICITY INFORMATION/ Lung tumors have been induced by zinc chromates and other hexavalent chromium compounds in laboratory animals and zinc-chromate has shown mutagenic activity in bacterial test systems. Epidemiologic studies have shown an increased incidence of lung cancer among chromate pigment workers, however, the number of cancer cases was small and the concentrations of zinc-chromate were not known. The authors conclude that exposure to zinc chromates appears to be associated with an increased cancer risk.

Chromic acid (H2Cr2O7), zinc salt (1:1): INACTIVE|R - indicates a substance that is the subject of a TSCA section 6 risk management rule.