Glenvastatin
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Glenvastatin
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CAS No:
122254-45-9
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Formula:
C27H26FNO3
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Chemical Name:
Glenvastatin
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Synonyms:
2H-Pyran-2-one,6-[(1E)-2-[4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-,(4R,6S)-;2H-Pyran-2-one,6-[2-[4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-,[4R-[4α,6β(E)]]-;(4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one;HR 780;Glenvastin;(4R,6S)-6-[(E)-2-[4-(p-Fluorophenyl)-2-isopropyl-6-phenyl-3-pyridyl]vinyl]tetrahydro-4-hydroxy-2H-pyran-2-one;Glenvastatin
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CAS No:
Drug Information
Compounds that inhibit HYDROXYMETHYLGLUTARYL COA REDUCTASES. They have been shown to directly lower CHOLESTEROL synthesis. (See all compounds classified as Hydroxymethylglutaryl-CoA Reductase Inhibitors.)
HR 780
Computed Properties
Molecular Weight:431.5
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:431.18967185
Monoisotopic Mass:431.18967185
Topological Polar Surface Area:59.4
Heavy Atom Count:32
Complexity:639
Defined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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