8-OH-DPAT
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8-OH-DPAT
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CAS No:
78950-78-4
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Formula:
C16H25NO
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Chemical Name:
8-OH-DPAT
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Synonyms:
1-Naphthalenol,7-(dipropylamino)-5,6,7,8-tetrahydro-;7-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol;8-Hydroxy-2-(di-n-propylamino)tetralin;8-Hydroxy-N,N-dipropyl-2-aminotetralin;PAT;8-Hydroxy-2-(dipropylamino)tetralin;8-OH-DPAT;8-Hydroxy-DPAT;dl-8-Hydroxy-2-(dipropylamino)tetralin;(±)-8-Hydroxy-2-(di-n-propylamino)tetralin;(±)-7-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol;(±)-8-Hydroxy-N,N-dipropyl-2-aminotetralin;(±)-8-OH-DPAT;(±)-8-Hydroxy-2-(dipropylamino)tetralin;(+)-8-Hydroxy-2-(di-n-propylamino)tetralin;105558-30-3;122341-76-8;142272-99-9;80300-08-9
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CAS No:
Description
8-OH-DPAT is a tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively It has a role as a serotonergic antagonist. It is a member of tetralins, a member of phenols and a tertiary amino compound. It derives from a hydride of a tetralin.|A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
Drug Information
Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)
8-Hydroxy-2-(di-n-propylamino)tetralin
Computed Properties
Molecular Weight:247.38
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:247.193614421
Monoisotopic Mass:247.193614421
Topological Polar Surface Area:23.5
Heavy Atom Count:18
Complexity:237
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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