Zofenoprilat
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Zofenoprilat
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CAS No:
75176-37-3
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Formula:
C15H19NO3S2
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Chemical Name:
Zofenoprilat
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Synonyms:
L-Proline,1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-,(4S)-;L-Proline,1-(3-mercapto-2-methyl-1-oxopropyl)-4-(phenylthio)-,[1(R*),2α,4α]-;(4S)-1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline;SQ 26333;Zofenoprilat
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CAS No:
Description
Zofenoprilat is a proline derivative that is 4-(phenylsulfanyl)-L-proline in which the amine proton is replaced by a (2S)-2-methyl-3-sulfanylpropanoyl group. The active metabolite of zofenopril. It has a role as an anticonvulsant, an apoptosis inhibitor, a cardioprotective agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, a drug metabolite and a vasodilator agent. It is a N-acyl-L-amino acid, an aryl sulfide, a thiol and a L-proline derivative. It is a conjugate acid of a zofenoprilat(1-).
Computed Properties
Molecular Weight:325.5
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:325.08063582
Monoisotopic Mass:325.08063582
Topological Polar Surface Area:83.9
Heavy Atom Count:21
Complexity:385
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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