 Home > Encyclopedia > Norverapamil

Norverapamil

Norverapamil structure

CAS No:
67018-85-3
Formula:
C26H36N2O4
Chemical Name:
Norverapamil
Synonyms:
Benzeneacetonitrile,α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-;Valeronitrile,5-[(3,4-dimethoxyphenethyl)amino]-2-(3,4-dimethoxyphenyl)-2-isopropyl-;α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzeneacetonitrile;D 591;Norverapamil;(±)-Norverapamil;2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile;73980-36-6
Categories:
Organic Chemistry > Amides

Description

2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile is a secondary amino compound that is 3,4-dimethoxyphenylethylamine in which one of the hydrogens attached to the nitrogen has been replaced by a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group. It is an aromatic ether, a nitrile, a polyether and a secondary amino compound.

Norverapamil Basic Attributes

Molecular Weight：

477.03600

Exact Mass：

440.58

EC Number：

266-544-8

NSC Number：

672815

Characteristics

PSA：

72.74000

XLogP3：

5.94378

Boiling Point：

586.1ºC at 760 mmHg

Flash Point：

308.2ºC

Collision Cross Section：

207.3 Å² [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]

Safety Information

GHS Classification：

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH：

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

Metabolism/Metabolites：

Norverapamil has known human metabolites that include 2-(3,4-dimethoxyphenyl)acetaldehyde, 5-Amino-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile, and D-715 (PR-22).

MeSH Entry Terms：

D 591

Computed Properties

Molecular Weight:440.6
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:13
Exact Mass:440.26750763
Monoisotopic Mass:440.26750763
Topological Polar Surface Area:72.7
Heavy Atom Count:32
Complexity:577
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Norverapamil

REFSYN BIOSCIENCES PVT LTD Contact Supplier

IN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Drug Impurity

N-desmethyl verapamil

CAS No.: 67018-85-3

Inquiry