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Home > Encyclopedia > 3-(Nitroxymethyl)phenyl 2-acetoxybenzoate

3-(Nitroxymethyl)phenyl 2-acetoxybenzoate

3-(Nitroxymethyl)phenyl 2-acetoxybenzoate structure

3-(Nitroxymethyl)phenyl 2-acetoxybenzoate 

structure
  • CAS No:

    175033-36-0

  • Formula:

    C16H13NO7

  • Chemical Name:

    3-(Nitroxymethyl)phenyl 2-acetoxybenzoate

  • Synonyms:

    Benzoic acid,2-(acetyloxy)-,3-[(nitrooxy)methyl]phenyl ester;NCX 4016;3-(Nitroxymethyl)phenyl 2-acetoxybenzoate;2-Acetoxybenzoic acid 3-nitrooxymethylphenyl ester;Nitroaspirin;3-((Nitrooxy)methyl)phenyl 2-acetoxybenzoate;190442-10-5

Description

2-acetyloxybenzoic acid [3-(nitrooxymethyl)phenyl] ester is a carbonyl compound.|Nitroaspirin has been investigated for the treatment of Intermittent Claudication.

3-(Nitroxymethyl)phenyl 2-acetoxybenzoate Basic Attributes

331.27700

331.28

EH04H13L6B

Characteristics

107.65000

3.06260

1.347g/cm3

61-62ºC

499.3ºC at 760mmHg

214.3ºC

1.58

4.21E-10mmHg at 25°C

Drug Information

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)|Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES. (See all compounds classified as Cysteine Proteinase Inhibitors.)|Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)|Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN. (See all compounds classified as Fibrinolytic Agents.)

2-acetoxybenzoate-2-(1-nitroxymethyl)phenyl ester

Computed Properties

Molecular Weight:331.28
XLogP3:2.9
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:331.06920175
Monoisotopic Mass:331.06920175
Topological Polar Surface Area:108
Heavy Atom Count:24
Complexity:462
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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