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Propidium

Propidium structure

Propidium 

structure
  • CAS No:

    36015-30-2

  • Formula:

    C27H34N4

  • Chemical Name:

    Propidium

  • Synonyms:

    Phenanthridinium,3,8-diamino-5-[3-(diethylmethylammonio)propyl]-6-phenyl-;3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium;Propidium

Description

Propidium is a quaternary ammonium ion and a member of phenanthridines. It has a role as an intercalator and a fluorochrome.|Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Propidium Basic Attributes

414.6 g/mol

414.27834710 g/mol

74NX23J96Y

DTXSID20189583

Characteristics

55.9 Ų

Drug Information

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)|Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA. (See all compounds classified as Intercalating Agents.)|Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)

Diiodide, Propidium

Computed Properties

Molecular Weight:414.6
XLogP3:4.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:414.27834710
Monoisotopic Mass:414.27834710
Topological Polar Surface Area:55.9
Heavy Atom Count:31
Formal Charge:2
Complexity:555
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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