4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine
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![4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/9596af8acd454365b68fd2ad477f3c56.png "4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine")
4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine
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CAS No:
165806-53-1
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Formula:
C18H19FN6
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Chemical Name:
4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine
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Synonyms:
5-(2-amino-pyrimidinyl)-4-(4-fluorophenyl)-1-(4-piperidinyl)imidazole;SB 220025;SB-220025;SB220025;SB220025;sb 220025;165806-53-1;3erk;SB-220025;4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]pyrimidin-2-amine;UNII-MX95H97VRG;MX95H97VRG;CHEMBL274064;CHEBI:82713;4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE;SB4;4-[5-(4-fluorophenyl)-3-(4-piperidyl)imidazol-4-yl]pyrimidin-2-amine;SB-220025-A;1-(4-piperidinyl)-4-(4-fluorophenyl)-5-(2-(amino)-4-pyrimidinyl)imidazole;1-(4-piperidinyl)-4-(4-fluorophenyl)-5-[2-(amino)-4-pyrimidinyl]imidazole;Kinome_3166;1bl7;SCHEMBL173441;GTPL6038;ZINC7258;BDBM15239;HMS3229M12;NSC756416;NSC756417;5-(2-Amino-4-pyrimidinyl)-4-(4-fluorophenyl)-1-(4-piperidinlyl)imidazole;AKOS017344571;CCG-206879;DB04338;NSC-756416;NSC-756417;NCGC00165900-01;NCGC00165900-02;NCGC00165900-03;AB01092383-01;AB01092383-02;J-010231;Q27088707;1-(4-piperidinyl)-4-(4-fluorophenyl)-5-[2-(amino)-4-pyrimdinyl]imidazole;1-(4-piperidinyl)-4-(4-fluorophenyl)-5-[2-(amino)-4pyrimidinyl]imidazole;4-[1-(Piperidine-4-yl)-4-(4-fluorophenyl)-5-imidazolyl]pyrimidine-2-amine;2-Pyrimidinamine, 4-(4-(4-fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl)-;4-(4-(4-Fluorophenyl)-1-(4-piperidinyl)-1H-imidazol-5-yl)-2-pyrimidinamine;4-[4-(4-fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]pyrimidin-2-amine
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CAS No:
Description
SB220025 is am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively. It has a role as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor, an angiogenesis inhibitor and an anti-inflammatory agent. It is a member of piperidines, an organofluorine compound, an aminopyrimidine and a member of imidazoles.
4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine Basic Attributes
338.4 g/mol
338.16552279 g/mol
MX95H97VRG
Safety Information
|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Computed Properties
Molecular Weight:338.4
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:338.16552279
Monoisotopic Mass:338.16552279
Topological Polar Surface Area:81.6
Heavy Atom Count:25
Complexity:424
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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