2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine
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![2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/fbac78e17bdd4a52a26979cc7c5ed978.png "2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine")
2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine
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CAS No:
73384-60-8
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Formula:
C14H13N3O2S
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Chemical Name:
2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine
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Synonyms:
3H-Imidazo[4,5-b]pyridine,2-[2-methoxy-4-(methylsulfinyl)phenyl]-;1H-Imidazo[4,5-b]pyridine,2-[2-methoxy-4-(methylsulfinyl)phenyl]-;2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine;AR-L 115BS;Vardax;Sulmazole;AR-L 115;AR-L;115BS;112363-11-8;134250-42-3
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CAS No:
Description
Sulmazole is an imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardiotonic agent. It has a role as a cardiotonic drug, an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor and an adenosine A1 receptor antagonist. It is an imidazopyridine and a sulfoxide.
2-[2-Methoxy-4-(methylsulfinyl)phenyl]-3H-imidazo[4,5-b]pyridine Basic Attributes
287.34 g/mol
287.34
277-406-1
757867
DTXSID1040617
Characteristics
87.1 Ų
1.18 (LogP)
203-205 °C
166.4 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases. (See all compounds classified as Phosphodiesterase Inhibitors.)|Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)
2-((2-methoxy-4-methylsulfinyl)phenyl)-H-imidazo(4,5-b)pyridine
Computed Properties
Molecular Weight:287.34
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:287.07284784
Monoisotopic Mass:287.07284784
Topological Polar Surface Area:87.1
Heavy Atom Count:20
Complexity:368
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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