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Home > Encyclopedia > 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1)

2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1)

2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) structure

2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) 

structure
  • CAS No:

    15148-80-8

  • Formula:

    C14H22ClNO2.ClH

  • Chemical Name:

    2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1)

  • Synonyms:

    2-Propanol,1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-,hydrochloride (1:1);2-Propanol,1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]-,hydrochloride;2-Propanol,1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-,hydrochloride;KL 255;1-(6′-Chloro-3′-methylphenoxy)-3-tert-butylaminopropanol,hydrochloride;1-tert-Butylamino-3-(6-chloro-m-tolyloxy)-2-propanol hydrochloride;3-tert-Butylamino-1-(6-chloro-3-methylphenoxy)propan-2-ol hydrochloride;Betadrenol;1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol hydrochloride;SKF 16805A;Betadrenol hydrochloride;(-)-KL 255;Bupranolol hydrochloride;Betadran;(±)-Kl 255;dl-KL 255;dl-Bupranolol hydrochloride;Looser;Panimit;B 1312;23284-25-5

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

Bupranolol hydrochloride is an aromatic ether.|An adrenergic-beta-2 antagonist that has been used for cardiac arrhythmia, angina pectoris, hypertension, glaucoma, and as an antithrombotic.

2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) Basic Attributes

308.2 g/mol

307.1105844 g/mol

239-208-3

Characteristics

41.5 Ų

3.96910

220-222 °C

Drug Information

Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (See all compounds classified as Adrenergic beta-Antagonists.)|Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)

Betadrenol

Computed Properties

Molecular Weight:308.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:307.1105844
Monoisotopic Mass:307.1105844
Topological Polar Surface Area:41.5
Heavy Atom Count:19
Complexity:242
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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Guide of 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1)

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