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Disoxaril

Disoxaril structure

Disoxaril 

structure
  • CAS No:

    87495-31-6

  • Formula:

    C20H26N2O3

  • Chemical Name:

    Disoxaril

  • Synonyms:

    Isoxazole,5-[7-[4-(4,5-dihydro-2-oxazolyl)phenoxy]heptyl]-3-methyl-;5-[7-[4-(4,5-Dihydro-2-oxazolyl)phenoxy]heptyl]-3-methylisoxazole;Win 51711;Disoxaril;98034-33-4

Description

Compound IV is an aromatic ether.|5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring. Known drug targets of 5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole include genome polyprotein.|Disoxaril is a compound with activity against human picornaviruses. Disoxaril binds to the hydrophobic pocket within the viral VP1 capsid protein and prevents structural transitions required for viral uncoating resulting in an inhibition of viral reproduction.

Disoxaril Basic Attributes

342.4 g/mol

342.43

FX8Q9PI4VP

DTXSID70236354

C81607

Characteristics

56.8 Ų

4.79 (LogP)

86-89 °C

Drug Information

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methylisoxazole

Computed Properties

Molecular Weight:342.4
XLogP3:4.4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:342.19434270
Monoisotopic Mass:342.19434270
Topological Polar Surface Area:56.8
Heavy Atom Count:25
Complexity:408
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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