Liarozole
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Liarozole
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CAS No:
115575-11-6
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Formula:
C17H13ClN4
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Chemical Name:
Liarozole
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Synonyms:
1H-Benzimidazole,6-[(3-chlorophenyl)-1H-imidazol-1-ylmethyl]-;1H-Benzimidazole,5-[(3-chlorophenyl)-1H-imidazol-1-ylmethyl]-;6-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole;Liarozole;145858-51-1
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CAS No:
Description
Liarozole is a member of benzimidazoles.|Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Drug Information
Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079) (See all compounds classified as Antineoplastic Agents, Hormonal.)|Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)|Compounds which inhibit or antagonize the biosynthesis or actions of androgens. (See all compounds classified as Androgen Antagonists.)|Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)
liarozole
Computed Properties
Molecular Weight:308.8
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:308.0828741
Monoisotopic Mass:308.0828741
Topological Polar Surface Area:46.5
Heavy Atom Count:22
Complexity:380
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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