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Home > Encyclopedia > 4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine

4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine

4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine structure

4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine 

structure
  • CAS No:

    173026-17-0

  • Formula:

    C10H13NSe

  • Chemical Name:

    4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine

  • Synonyms:

    BXT 51072;BXT-51072;ALT-2074;BXT-51072;UNII-634U7OUR4R;BXT 51072;173026-17-0;634U7OUR4R;4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine;SYI-2074;4,4-Dimethyl-3,4-dihydro-2H-1,2-benzoselenazine;SCHEMBL921152;CHEMBL4297259;DTXSID80169503;SYI 2074;DB05631;2H-1,2-Benzoselenazine, 3,4-dihydro-4,4-dimethyl-;Q27263560;3,4-Dihydro-4,4-dimethyl-2H-1-selena-2-azanaphthalene

Description

An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, primarily because of its ability to mimic the function of glutathione peroxidase.

4,4-dimethyl-2,3-dihydro-1,2-benzoselenazine Basic Attributes

226.19 g/mol

227.02132 g/mol

634U7OUR4R

DTXSID80169503

Characteristics

12 Ų

Toxicity

IC50 2.0–2.6 μM.

Drug Information

Investigated for use/treatment in cardiovascular disorders and diabetes mellitus type 1 and 2.

24.15 (+/-2.38) (ml min-1kg-1).

2.08 (+/-0.17) hours.

BXT 51072

Computed Properties

Molecular Weight:226.19
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:227.02132
Monoisotopic Mass:227.02132
Topological Polar Surface Area:12
Heavy Atom Count:12
Complexity:167
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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